Vergleich

Biotinylated Human Integrin alpha 8 beta 1 (ITGA8&ITGB1) Heterodimer Protein, His,Avitag™&Tag Free Europäischer Partner

ArtNr IT1-H82Wb-25ug
Hersteller ACROBiosystems
Menge 25 ug
Quantity options 200 ug 25 ug
Kategorie
Typ Proteins Recombinant
Format Solid
Specific against Human (Homo sapiens)
Host HEK293
Konjugat/Tag Biotin, HIS, Avi
Purity 90%
Citations (1) Müller U, et al., 1995, Mol Biol Cell 6(4):433-48. (2) Schnapp LM, et al., 1995, J Biol Chem 270(39):23196-202. (3) Marek I, et al., 2014, Cell Adh Migr 8(4): 389-395.
NCBI NP 003629.2 , NP_002202.2
ECLASS 10.1 32160409
ECLASS 11.0 32160409
UNSPSC 12352202
Alias Integrin alpha 8 beta 1,ITGA8&ITGB1
Versandbedingung Raumtemperatur
Lieferbar
Manufacturer - Category
Protein / MABSol® Biotin Labeled Proteins
Manufacturer - Conjugate / Tag
C-10xHis, C-Avi | Native, Biotin-labeled
Shipping Temperature
RT
Storage Conditions
-20°C
Molecular Weight
116.4 kDa (ITGA8) & 83.7 kDa (ITGB1)
Manufacturer - Format
Powder
Description
Biotinylated Human ITGA8&ITGB1 Heterodimer Protein, His, Avitag&Tag Free (IT1-H82Wb) is expressed from human 293 cells (HEK293). It contains AA Phe 39 - Leu 1012 (ITGA8) & Gln 21 - Asp 728 (ITGB1) (Accession # P53708-1 (ITGA8) & P05556-1 (ITGB1)).
Background
Human Integrin alpha 8 beta 1 Heterodimer Protein consists of ITGA8 and ITGB1. The integrin alpha 8 subunit, isolated by low stringency hybridization, is a novel integrin subunit that associates with beta 1. The recently identified alpha 8 integrin subunit associates with beta 1 and is predominantly expressed in smooth muscle and other contractile cells in adult tissues, and in mesenchymal and neural cells during development. In addition, Integrin alpha 8 beta 1 is a receptor for fibronectin and can promote attachment, cell spreading, and neurite outgrowth on fibronectin.
Molecule
Integrin alpha 8 beta 1
Exp Region
Phe 39 - Leu 1012 (ITGA8) & Gln 21 - Asp 728 (ITGB1)
Characteristics
Biotinylated Human ITGA8&ITGB1 Heterodimer Protein, His, Avitag&Tag Free, produced by co-expression of ITGA8 and ITGB1, has a calculated MW of 116.4 kDa (ITGA8) and 83.7 kDa (ITGB1). Subunit ITGA8 is fused with an acidic tail at the C-terminus and followed by a polyhistidine tag and an Avi tag and subunit ITGB1 contains no tag but a basic tail at the C-terminus. The non-reducing (NR) protein migrates as 140-150 kDa (ITGA8) and 100-115 kDa (ITGB1) respectively due to glycosylation.
Endotoxin
1.0 EU per μg
Buffer
50 mM Tris, 150 mM NaCl, pH7.5
Stability
● -20°C to -70°C for 12 months in lyophilized state; ● -70°C for 3 months under sterile conditions after reconstitution._x000D_For long term storage, the product should be stored at lyophilized state at -20°C or lower.
Protectant
trehalose

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

Menge: 25 ug
Lieferbar: In stock
lieferbar

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