ArtNr |
ITG-MM1V8-500UG |
Hersteller |
KactusBio
|
Menge |
500 ug |
Quantity options |
100 ug
500 ug
|
Kategorie |
|
Typ |
Proteins Recombinant |
Format |
Lyophilized |
Specific against |
Mouse (Murine, Mus musculus) |
Host |
HEK293 |
Konjugat/Tag |
HIS |
Purity |
> 95% as determined by Bis-Tris PAGE; > 95% as determined by HPLC |
Formula |
Lyophilized from 0.22μm filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization. |
Sequence |
Phe31-Val988(ITGAV)acidic tail & Gly22-Ser679(ITGB8)basic tail |
ECLASS 10.1 |
32160409 |
ECLASS 11.0 |
32160409 |
UNSPSC |
12352202 |
Alias |
Integrin alpha V beta 8;ITGAV&ITGB8 |
Lieferbar |
|
Manufacturer - Product Type |
Recombinant Protein |
Description |
Recombinant Mouse Integrin alpha V beta 8 (ITGAV&ITGB8) Heterodimer Protein is expressed from HEK293 with His tag at the C-Terminus.It contains Phe31-Val988(ITGAV) acidic tail&Gly22-Ser679(ITGB8) basic tail. |
Background |
Deletions of the genes encoding the integrin αVβ8 (Itgav, Itgb8) have been shown to result in abnormal vascular development in the CNS, including prenatal and perinatal hemorrhage. Other work has indicated that a major function of this integrin in vivo is to promote TGFβ activation. |
Endotoxin |
Less than 1 EU per μg by the LAL method. |
Molecular Weight |
The protein has a predicted MW of 111.6(ITGAV)&76.6(ITGB8) kDa. Due to glycosylation, the protein migrates to 80-140 kDa based on Bis-Tris PAGE result. |
Target |
Integrin alpha V beta 8 (ITGAV&ITGB8) Heterodimer |
Manufacturer - Tag |
C-His |
Stability and Storage |
-20 to -80°C for 24 months as supplied from date of receipt; -80°C for 3-6 months after reconstitution; 2-8°C for 2-7 days after reconstitution; Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles. |
Shipping |
Shipped at ambient temperature. |
Formulation |
Lyophilized from 0.22μm filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization. |
Reconstitution |
Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/ml is recommended. Dissolve the lyophilized protein in distilled water. |
Biotinylated |
no |
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