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Mouse Integrin alpha V beta 8 (ITGAV&ITGB8) Heterodimer Protein (ITG-MM1V8)

Mouse Integrin alpha V beta 8 (ITGAV&ITGB8) Heterodimer Protein (ITG-MM1V8)

Item no.	ITG-MM1V8-500UG
Manufacturer	KactusBio
Amount	500 ug
Quantity options	100 ug 500 ug
Category	Peptides & Proteins Recombinant Proteins
Type	Proteins Recombinant
Format	Lyophilized
Specific against	Mouse (Murine, Mus musculus)
Host	HEK293
Conjugate/Tag	HIS
Purity	> 95% as determined by Bis-Tris PAGE; > 95% as determined by HPLC
Formula	Lyophilized from 0.22μm filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization.
Sequence	Phe31-Val988(ITGAV)acidic tail & Gly22-Ser679(ITGB8)basic tail
ECLASS 10.1	32160409
ECLASS 11.0	32160409
UNSPSC	12352202
Alias	Integrin alpha V beta 8；ITGAV&ITGB8
Available
Manufacturer - Product Type	Recombinant Protein
Description	Recombinant Mouse Integrin alpha V beta 8 (ITGAV&ITGB8) Heterodimer Protein is expressed from HEK293 with His tag at the C-Terminus.It contains Phe31-Val988(ITGAV) acidic tail&Gly22-Ser679(ITGB8) basic tail.
Background	Deletions of the genes encoding the integrin αVβ8 (Itgav, Itgb8) have been shown to result in abnormal vascular development in the CNS, including prenatal and perinatal hemorrhage. Other work has indicated that a major function of this integrin in vivo is to promote TGFβ activation.
Endotoxin	Less than 1 EU per μg by the LAL method.
Molecular Weight	The protein has a predicted MW of 111.6(ITGAV)&76.6(ITGB8) kDa. Due to glycosylation, the protein migrates to 80-140 kDa based on Bis-Tris PAGE result.
Target	Integrin alpha V beta 8 (ITGAV&ITGB8) Heterodimer
Manufacturer - Tag	C-His
Stability and Storage	-20 to -80°C for 24 months as supplied from date of receipt; -80°C for 3-6 months after reconstitution; 2-8°C for 2-7 days after reconstitution; Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
Shipping	Shipped at ambient temperature.
Formulation	Lyophilized from 0.22μm filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization.
Reconstitution	Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/ml is recommended. Dissolve the lyophilized protein in distilled water.
Biotinylated	no

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

Request Data Sheet

ITG-MM1V8-500UG-datasheet.pdf

ITG-MM1V8-500UG-safety-datasheet.pdf