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Human&Mouse Chimeric WT-1 (HLA-A*02:01) Tetramer Protein (MHC-HM425T)

Human&Mouse Chimeric WT-1 (HLA-A*02:01) Tetramer Protein (MHC-HM425T)

ArtNr	MHC-HM425T-500UG
Hersteller	KactusBio
Menge	500 ug
Quantity options	100 ug 500 ug
Kategorie	Oncology By Cell Type Blastoma Carcinoma Glioma Hematology Leukemia Lymphoma Myeloma Melanoma Peptides & Proteins Recombinant Proteins Adenocarcinoma Myelofibrosis Mesothelioma Astrocytoma
Typ	Proteins Recombinant
Format	Liquid
Specific against	other
Host	HEK293
Konjugat/Tag	HIS, Avi
Purity	> 95% as determined by Tris-Bis PAGE;> 95% as determined by HPLC
Formula	Supplied as 0.22μm filtered solution in PBS, 200mM L-arginine (pH 7.4).
Sequence	Gly25-Thr206(Human HLA-A02:01 α1&α2) & Asp140-Lys241(Mouse HLA-A02:01 α3), Ile21-Met119(B2M)and RMFPNAPYL peptide
NCBI	RMFPNAPYL
ECLASS 10.1	32160409
ECLASS 11.0	32160409
UNSPSC	12352202
Alias	MHC, WT1, RMF, AWT1, GUD, NPHS4GUD, WAGR, WIT-2, WT33
Lieferbar
Manufacturer - Conjugate / Tag	C-His-Avi
Shipping Temperature	Shipped with blue ice
Storage Conditions	Valid for 12 months from date of receipt when stored at -80°C. Recommend to aliquot the protein into smaller quantities for optimal storage. Please avoid repeated freeze-thaw cycles.
Molecular Weight	The protein has a predicted MW of 258 kDa. Due to glycosylation, the protein migrates to 260-265 kDa under Non reducing (N) condition based on Tris-Bis PAGE result.
Description	Recombinant Human&Mouse Chimeric WT-1(HLA-A02:01) Tetramer Protein is expressed from HEK293 with His tag and Avi tag at the C-terminal, tetramer is assembled by biotinylated monomer and streptavidin.It contains Gly25-Thr206(Human HLA-A02:01 α1&α2) & Asp140-Lys241(Mouse HLA-A*02:01 α3), Ile21-Met119 (B2M) and RMFPNAPYL peptide.
Background	NY-ESO-1 or New York esophageal squamous cell carcinoma 1 is a well-known cancer-testis antigen (CTAs) with re-expression in numerous cancer types. Its ability to elicit spontaneous humoral and cellular immune responses, together with its restricted expression pattern, have rendered it a good candidate target for cancer immunotherapy.
Endotoxin	Less than 1EU per μg by the LAL method.
Formulation	Supplied as 0.22μm filtered solution in PBS, 200mM L-arginine (pH 7.4).
Biotinylated	no
Activity	Immobilized Human&Mouse Chimeric WT-1 (HLA-A02:01) Tetramer, His Tag at 1μg/ml (100μl/Well) on the plate. Dose response curve for Anti-WT-1 (HLA-A02:01) Antibody, hFc Tag with the EC50 of 18.7ng/ml determined by ELISA. See testing image for detail.

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

Arbeitsanleitung (Data Sheet) anfordern

MHC-HM425T-500UG-datasheet.pdf

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Einfache Bestellung Periodische Bestellung

Menge: 500 ug

lieferbar

Lieferung vsl. bis 25.12.2025

Express-Lieferung: 6 Tage sparen

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