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Recombinant human GRP94/HSP90B1 protein

ArtNr NKM-ATGP0276-500ug
Hersteller NKMAX
Menge 500 ug
Quantity options 100 ug 20 ug 500 ug
Kategorie
Typ Proteins Recombinant
Format Liquid
Applikationen SDS-PAGE
Specific against Human (Homo sapiens)
Host E.coli
Konjugat/Tag HIS
Purity > 90% by SDS-PAGE
Sequence <MRGSHHHHHH GMASMTGGQQ MGRDLYDDDD KDRWGSM>DDE VDVDGTVEED LGKSREGSRT DDEVVQREEE AIQLDGLNAS QIRELREKSE KFAFQAEVNR MMKLIINSLY KNKEIFLREL ISNASDALDK IRLISLTDEN ALSGNEELTV KIKCDKEKNL LHVTDTGVGM TREELVKNLG TIAKSGTSEF LNKMTEAQED GQSTSELIGQ FGVGFYSAFL VADKVIVTSK
Citations Randow F., et al. (2001). Nat Cell Biol. 3(10):E231.
Li Z., et al. (2002). Front Biosci. 7:d731-51.

Yoshimura C, et al. Thermodynamic Dissection of Potency and Selectivity of Cytosolic Hsp90 Inhibitors. (J Med Chem. 2021){https://pubmed.ncbi.nlm.nih.gov/33621080/}
NCBI NP_003290.1
ECLASS 10.1 32160409
ECLASS 11.0 32160409
UNSPSC 12352202
Alias Tumor rejection antigen GP96,Tumor rejection antigen 1,TRA1,Stress inducible tumor rejection antigen GP96,HSP90B1,Heat shock protein 90 kDa beta member 1,GRP94,GRP 9,GP96 homolog,GP96,Glucose regulated protein 94kDa,Endothelial cell (HBMEC) glycoprotein,Endoplasmin,ECGP,94 kDa glucose-regulated protein
Similar products GRP94, HSP90B1, TRA1, Endoplasmin, 94 kDa glucose-regulated protein, Heat shock protein 90 kDa beta member 1, Tumor rejection antigen 1, ECGP, GP96, 94 kDa glucose regulated protein, Glucose regulated protein 94kDa, Stress inducible tumor rejection antigen GP96, Endothelial cell (HBMEC) glycoprotein, Tumor rejection antigen GP96, GRP 9, GRP9, GP96 homolog, 94kDa glucose regulated protein, 94kDa glucose-regulated protein, ATGP0276-10ug, ATGP0276-20ug, ATGP0276-50ug, ATGP0276-100ug, ATGP0276-250ug, ATGP0276-500ug, ATGP0276-1mg, ATGP0276-010, ATGP0276-020, ATGP0276-050, ATGP0276-100, ATGP0276-250, ATGP0276-500, ATGP0276-01M
Lieferbar
Manufacturer - Type
Recombinant Protein
Storage Conditions
Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
Molecular Weight
94.4 kDa (819aa)
Description
GRP94, also known as Heat shock protein 90kDa beta, member 1 (HSP90B1), is an abundant resident endoplasmic reticulum (ER) lumenal stress protein which together with cytosolic Hsp90 belongs to the Hsp90 family of molecular chaperones. It plays an important role in maintaining protein homeostasis in the secretory pathway. Also, GRP94 can function in the intracellular trafficking of peptides from the extracellular space to the MHC class I antigen processing pathway of antigen presentation cells. Recombinant human GRP94 protein, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography.
Concentration
1mg/ml (determined by Bradford assay)
Formulation
Liquid in. 20mM Tris-HCl buffer (pH 8.0) containing 1mM DTT, 1mM EDTA, 0.1M NaCl, 10% glycerol,
Antigen Species
Human
Gene Category
Heat Shock Proteins
Domain
22-803aa
Species of Protein
Human
Manufacturer - Search Terms
Tumor rejection antigen GP96, Tumor rejection antigen 1, TRA1, Stress inducible tumor rejection antigen GP96, HSP90B1, Heat shock protein 90 kDa beta member 1, GRP94, GRP 9, GRP9, GP96 homolog, GP96, Glucose regulated protein 94kDa, Endothelial cell (HBMEC) glycoprotein, Endoplasmin, ECGP, 94 kDa glucose-regulated protein, 94 kDa glucose regulated protein, 94kDa glucose regulated protein, 94kDa glucose-regulated protein, ATGP0276-10ug, ATGP0276-20ug, ATGP0276-50ug, ATGP0276-100ug, ATGP0276-250ug, ATGP0276-500ug, ATGP0276-1mg, ATGP0276-010, ATGP0276-020, ATGP0276-050, ATGP0276-100, ATGP0276-250, ATGP0276-500, ATGP0276-01M
Manufacturer - Alternative Names
Tumor rejection antigen GP96, Tumor rejection antigen 1, TRA1, Stress inducible tumor rejection antigen GP96, HSP90B1, Heat shock protein 90 kDa beta member 1, GRP94, GRP 9, GP96 homolog, GP96, Glucose regulated protein 94kDa, Endothelial cell (HBMEC) glycoprotein, Endoplasmin, ECGP, 94 kDa glucose-regulated protein

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

Menge: 500 ug
Lieferbar: In stock
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