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Recombinant human CDC42 protein

ArtNr NKM-ATGP0395-20ug
Hersteller NKMAX
Menge 20 ug
Quantity options 100 ug 20 ug 500 ug
Kategorie
Typ Proteins Recombinant
Format Liquid
Applikationen SDS-PAGE
Specific against Human (Homo sapiens)
Host E.coli
Konjugat/Tag T7 Epitope
Purity > 95% by SDS-PAGE
Sequence <MASMTGGQQM GRGSH>MQTIK CVVVGDGAVG KTCLLISYTT NKFPSEYVPT VFDNYAVTVM IGGEPYTLGL FDTAGQEDYD RLRPLSYPQT DVFLVCFSVV SPSSFENVKE KWVPEITHHC PKTPFLLVGT QIDLRDDPST IEKLAKNKQK PITPETAEKL ARDLKAVKYV ECSALTQKGL KNVFDEAILA ALEPPEPKKS RRC
Citations Kathryn P., et al. (2008) J Cell Biol. 183(6):1129-1143.
Li R., et al. (1997) J Biol Chem. 272(52):32830-5.
NCBI NP_001782
ECLASS 10.1 32160409
ECLASS 11.0 32160409
UNSPSC 12352202
Alias Cell division cycle 42 isoform 1,G25K,Cell division cycle 42 isoform 1 CDC42Hs,Cell division cycle 42,Small GTP binding protein CDC42.
Similar products CDC42, ATGP0395-10ug, ATGP0395-20ug, ATGP0395-50ug, ATGP0395-100ug, ATGP0395-250ug, ATGP0395-500ug, ATGP0395-1mg, ATGP0395-10, ATGP0395-20, ATGP0395-50, ATGP0395-100, ATGP0395-250, ATGP0395-500, ATGP0395-1
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Manufacturer - Type
Recombinant Protein
Storage Conditions
Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
Molecular Weight
22.4 kDa (203aa) confirmed by MALDI-TOF
Description
Cell division cycle 42 isoform 1, also known as CDC42, is a small GTPase of the Rho-subfamily, which regulates signaling pathways that control diverse cellular functions including cell morphology, migration, endocytosis and cell cycle progression. Also, this protein could regulate actin polymerization through its direct binding to Neural Wiskott-Aldrich syndrome protein (N-WASP), which subsequently activates Arp2/3 complex. Loss of CDC42 function caused an increase in the endocytotic uptake of apical proteins, including apical polarity factors such as Crumbs. Recombinant human CDC42, fused to T7-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography techniques.
Concentration
1mg/ml (determined by Bradford assay)
Formulation
Liquid in. 20mM Tris-HCl buffer (pH 8.0) containing 1mM DTT, 10% glycerol, 2mM EDTA
Antigen Species
Human
Gene Category
Signal Transduction
Domain
1-188aa
Endotoxin
< 1 EU per 1ug of protein (determined by LAL method)
Species of Protein
Human
Manufacturer - Search Terms
CDC42, ATGP0395-10ug, ATGP0395-20ug, ATGP0395-50ug, ATGP0395-100ug, ATGP0395-250ug, ATGP0395-500ug, ATGP0395-1mg, ATGP0395-10, ATGP0395-20, ATGP0395-50, ATGP0395-100, ATGP0395-250, ATGP0395-500, ATGP0395-1

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

Menge: 20 ug
Lieferbar: In stock
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