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Recombinant human PKM protein

Recombinant human PKM protein

ArtNr	NKM-ATGP0429-20ug
Hersteller	NKMAX
Menge	20 ug
Quantity options	100 ug 20 ug 500 ug
Kategorie	Oncology Metabolism Glucose Homeostasis Assisted reproductive technologies Embryo manipulation Peptides & Proteins Recombinant Proteins SDS-PAGE By Organ Thyroid Cancer
Typ	Proteins Recombinant
Format	Liquid
Applikationen	SDS-PAGE
Specific against	Human (Homo sapiens)
Host	E.coli
Konjugat/Tag	HIS
Purity	> 95% by SDS-PAGE
Sequence	<MGSSHHHHHH SSGLVPRGSH> MSKPHSEAGT AFIQTQQLHA AMADTFLEHM CRLDIDSPPI TARNTGIICT IGPASRSVET LKEMIKSGMN VARLNFSHGT HEYHAETIKN VRTATESFAS DPILYRPVAV ALDTKGPEIR TGLIKGSGTA EVELKKGATL KITLDNAYME KCDENILWLD YKNICKVVEV GSKIYVDDGL ISLQVKQKGA DFLVTEVENG GSLGSKKGVN
Citations	Zwerschke W., et al. (2009). Exp Cell Res. 315(16):2765-74 Mazurek S., et al. (2007). Ernst Schering Found Symp Proc. (4):99-124.
NCBI	NP_002645.3
ECLASS 10.1	32160409
ECLASS 11.0	32160409
UNSPSC	12352202
Alias	Pyruvate kinase muscle isoform M2,Pyruvate kinase M1/2,Pyruvate kinase muscle,Cytosolic thyroid hormone-binding protein,CTHBP,Pyruvate kinase 2/3,Threonine-protein kinase PKM2,Thyroid hormone-binding protein 1,THBP1,Opa-interacting protein 3,OIP3,Tumor M2-PK,Tyrosine-protein kinase PKM2,PK2,PK3,PKM2,p58
Similar products	PKM2, PKM, PK2, PK3, Pyruvate kinase isozymes M1/M2, Pyruvate kinase 2/3, Tumor M2-PK, p58, M2-PK, pyruvate kinase, CTHBP, TCB, THBP1, Tumor Type M2 Pyruvate Kinase, Cytosolic thyroid hormone binding protein, OPA interacting protein 3, Pyruvate kinase muscle, Thyroid hormone binding protein cytosolic, pyruvate kinase muscle isoform M2, muscle isoform M2 OIP3, Tumour Type M2 Pyruvate Kinase, ATGP0429-10ug, ATGP0429-20ug, ATGP0429-50ug, ATGP0429-100ug, ATGP0429-500ug, ATGP0429-1mg, ATGP0429-250ug, ATGP0429-10, ATGP0429-20, ATGP0429-50, ATGP0429-100, ATGP0429-250, ATGP0429-500, ATGP0429-1
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Manufacturer - Type	Recombinant Protein
Manufacturer - Applications	SDS-PAGE, Enzyme Activity
Storage Conditions	Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
Molecular Weight	60.1 kDa (551aa)
Description	PKM2 is an isoenzyme of the glycolytic enzyme pyruvate kinase. This protein catalyzes the production of pyruvate and ATP from phosphoenolpyruvate. PKM2 interacting with Opa proteins, a bacterial outer membrane protein involved in gonococcal adherence to and invasion of human cells, is required for bacterial pathogenesis. It is specifically expressed at high levels in tumor cells, and can be measured in plasma of patients with advanced breast cancer. Recombinant human PKM2, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography.
Concentration	1mg/ml (determined by Bradford assay)
Formulation	Liquid in. 20mM Tris-HCl buffer (pH 8.0) containing 10% glycerol
Antigen Species	Human
Gene Category	Cancer
Domain	1-531aa
Endotoxin	< 1 EU per 1ug of protein (determined by LAL method)
Bioactivity Comment Only	Specific activity: > 25, 000pmol/min/ug. One unit will convert 1.0pmole of phospho(enol)pyruvate to pyruvate per minute at pH 7.5 at 37C.
Species of Protein	Human
Manufacturer - Search Terms	PKM2, pyruvate kinase muscle isoform M2, CTHBP, THBP1, p58, M2-PK, Tumor M2-PK, PK2, PK3, PKM, pyruvate kinase, muscle isoform M2 OIP3, PKM, TCB, OPA interacting protein 3, PKM2, Cytosolic thyroid hormone binding protein, Pyruvate kinase 2/3, Pyruvate kinase isozymes M1/M2, Pyruvate kinase muscle, Thyroid hormone binding protein cytosolic, Tumour Type M2 Pyruvate Kinase, Tumor Type M2 Pyruvate Kinase, ATGP0429-10ug, ATGP0429-20ug, ATGP0429-50ug, ATGP0429-100ug, ATGP0429-500ug, ATGP0429-1mg, ATGP0429-10ug, ATGP0429-20ug, ATGP0429-50ug, ATGP0429-100ug, ATGP0429-250ug, ATGP0429-500ug, ATGP0429-1mg, ATGP0429-10, ATGP0429-20, ATGP0429-50, ATGP0429-100, ATGP0429-250, ATGP0429-500, ATGP0429-1
Manufacturer - Alternative Names	Pyruvate kinase muscle isoform M2, Pyruvate kinase M1/2, Pyruvate kinase muscle, Cytosolic thyroid hormone-binding protein, CTHBP, Pyruvate kinase 2/3, Threonine-protein kinase PKM2, Thyroid hormone-binding protein 1, THBP1, Opa-interacting protein 3, OIP3, Tumor M2-PK, Tyrosine-protein kinase PKM2, PK2, PK3, PKM2, p58

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

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NKM-ATGP0429-20ug-datasheet.pdf

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Menge: 20 ug

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Lieferung vsl. bis 31.07.2025

Express-Lieferung: 6 Tage sparen

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