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Recombinant human FEN1 protein

ArtNr NKM-ATGP0442-500ug
Hersteller NKMAX
Menge 500 ug
Quantity options 100 ug 20 ug 500 ug
Kategorie
Typ Proteins Recombinant
Format Liquid
Applikationen SDS-PAGE
Specific against Human (Homo sapiens)
Host E.coli
Konjugat/Tag Untagged
Purity > 90% by SDS-PAGE
Sequence MGIQGLAKLI ADVAPSAIRE NDIKSYFGRK VAIDASMSIY QFLIAVRQGG DVLQNEEGET TSHLMGMFYR TIRMMENGIK PVYVFDGKPP QLKSGELAKR SERRAEAEKQ LQQAQAAGAE QEVEKFTKRL VKVTKQHNDE CKHLLSLMGI PYLDAPSEAE ASCAALVKAG KVYAAATEDM DCLTFGSPVL MRHLTASEAK KLPIQEFHLS RILQELGLNQ EQFVDLCILL GS
Citations Hakoyama T., et al. (2009) Nature. 462(7272):514-7.
Lal A., et al. (2009) Mol Cell. 35(5):610-25.
NCBI NP_004102.1
ECLASS 10.1 32160409
ECLASS 11.0 32160409
UNSPSC 12352202
Alias Flap structure-specific endonuclease 1,FEN-1,MF1,RAD2,Flap structure-specific endonuclease 1 DNase IV,Flap endonuclease 1,Flap structure specific endonuclease 1,hFEN1,Maturation factor 1
Similar products FEN1, FEN-1, MF1, RAD2, Flap endonuclease 1, hFEN1, Maturation factor 1, Flap structure-specific endonuclease 1, Flap structure specific endonuclease 1, Flap structure-specific endonuclease 1 DNase IV, ATGP0442-10ug, ATGP0442-20ug, ATGP0442-50ug, ATGP0442-100ug, ATGP0442-250ug, ATGP0442-500ug, ATGP0442-1mg, ATGP0442-10, ATGP0442-20, ATGP0442-50, ATGP0442-100, ATGP0442-250, ATGP0442-500, ATGP0442-1
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Manufacturer - Type
Recombinant Protein
Storage Conditions
Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
Molecular Weight
42.5 kDa (380aa) confirmed by MALDI-TOF
Description
FEN-1, also known as Flap structure-specific endonuclease 1, removes 5' overhanging flaps in DNA repair and processes the 5' ends of Okazaki fragments in lagging strand DNA synthesis. The protein is a member of the XPG/RAD2 endonuclease family and is one of ten proteins essential for cell-free DNA replication. FEN-1 is highly homologous to yeast Rad2. The C-terminal region of FEN-1 may bind to PCNA, thus allowing FEN-1 to function as an exonuclease in DNA replication. Recombinant human FEN-1 protein was expressed in E. coli and purified by using conventional chromatography techniques.
Concentration
1mg/ml (determined by Bradford assay)
Formulation
Liquid in. 20mM Tris-HCl buffer (pH 8.0) containing 1mM DTT 10% glycerol
Antigen Species
Human
Gene Category
Enzymes & Proteases
Domain
1-380aa
Species of Protein
Human
Manufacturer - Search Terms
FEN1, Flap structure-specific endonuclease 1, FEN-1, MF1, RAD2, Flap structure-specific endonuclease 1 DNase IV, Flap endonuclease 1, Flap structure specific endonuclease 1, hFEN1, Maturation factor 1, ATGP0442-10ug, ATGP0442-20ug, ATGP0442-50ug, ATGP0442-100ug, ATGP0442-250ug, ATGP0442-500ug, ATGP0442-1mg, ATGP0442-10, ATGP0442-20, ATGP0442-50, ATGP0442-100, ATGP0442-250, ATGP0442-500, ATGP0442-1

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

Menge: 500 ug
Lieferbar: In stock
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