Comparison

Recombinant human FEN1 protein

Item no. NKM-ATGP0442-500ug
Manufacturer NKMAX
Amount 500 ug
Quantity options 100 ug 20 ug 500 ug
Category
Type Proteins Recombinant
Format Liquid
Applications SDS-PAGE
Specific against Human (Homo sapiens)
Host E.coli
Conjugate/Tag Untagged
Purity > 90% by SDS-PAGE
Sequence MGIQGLAKLI ADVAPSAIRE NDIKSYFGRK VAIDASMSIY QFLIAVRQGG DVLQNEEGET TSHLMGMFYR TIRMMENGIK PVYVFDGKPP QLKSGELAKR SERRAEAEKQ LQQAQAAGAE QEVEKFTKRL VKVTKQHNDE CKHLLSLMGI PYLDAPSEAE ASCAALVKAG KVYAAATEDM DCLTFGSPVL MRHLTASEAK KLPIQEFHLS RILQELGLNQ EQFVDLCILL GS
Citations Hakoyama T., et al. (2009) Nature. 462(7272):514-7.
Lal A., et al. (2009) Mol Cell. 35(5):610-25.
NCBI NP_004102.1
ECLASS 10.1 32160409
ECLASS 11.0 32160409
UNSPSC 12352202
Alias Flap structure-specific endonuclease 1,FEN-1,MF1,RAD2,Flap structure-specific endonuclease 1 DNase IV,Flap endonuclease 1,Flap structure specific endonuclease 1,hFEN1,Maturation factor 1
Similar products FEN1, FEN-1, MF1, RAD2, Flap endonuclease 1, hFEN1, Maturation factor 1, Flap structure-specific endonuclease 1, Flap structure specific endonuclease 1, Flap structure-specific endonuclease 1 DNase IV, ATGP0442-10ug, ATGP0442-20ug, ATGP0442-50ug, ATGP0442-100ug, ATGP0442-250ug, ATGP0442-500ug, ATGP0442-1mg, ATGP0442-10, ATGP0442-20, ATGP0442-50, ATGP0442-100, ATGP0442-250, ATGP0442-500, ATGP0442-1
Available
Manufacturer - Type
Recombinant Protein
Storage Conditions
Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
Molecular Weight
42.5 kDa (380aa) confirmed by MALDI-TOF
Description
FEN-1, also known as Flap structure-specific endonuclease 1, removes 5' overhanging flaps in DNA repair and processes the 5' ends of Okazaki fragments in lagging strand DNA synthesis. The protein is a member of the XPG/RAD2 endonuclease family and is one of ten proteins essential for cell-free DNA replication. FEN-1 is highly homologous to yeast Rad2. The C-terminal region of FEN-1 may bind to PCNA, thus allowing FEN-1 to function as an exonuclease in DNA replication. Recombinant human FEN-1 protein was expressed in E. coli and purified by using conventional chromatography techniques.
Concentration
1mg/ml (determined by Bradford assay)
Formulation
Liquid in. 20mM Tris-HCl buffer (pH 8.0) containing 1mM DTT 10% glycerol
Antigen Species
Human
Gene Category
Enzymes & Proteases
Domain
1-380aa
Species of Protein
Human
Manufacturer - Search Terms
FEN1, Flap structure-specific endonuclease 1, FEN-1, MF1, RAD2, Flap structure-specific endonuclease 1 DNase IV, Flap endonuclease 1, Flap structure specific endonuclease 1, hFEN1, Maturation factor 1, ATGP0442-10ug, ATGP0442-20ug, ATGP0442-50ug, ATGP0442-100ug, ATGP0442-250ug, ATGP0442-500ug, ATGP0442-1mg, ATGP0442-10, ATGP0442-20, ATGP0442-50, ATGP0442-100, ATGP0442-250, ATGP0442-500, ATGP0442-1

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

Amount: 500 ug
Available: In stock
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