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Recombinant human FEN1 protein

Recombinant human FEN1 protein

Item no.	NKM-ATGP0442-500ug
Manufacturer	NKMAX
Amount	500 ug
Quantity options	100 ug 20 ug 500 ug
Category	Oncology By Cell Type Peptides & Proteins Recombinant Proteins SDS-PAGE
Type	Proteins Recombinant
Format	Liquid
Applications	SDS-PAGE
Specific against	Human (Homo sapiens)
Host	E.coli
Conjugate/Tag	Untagged
Purity	> 90% by SDS-PAGE
Sequence	MGIQGLAKLI ADVAPSAIRE NDIKSYFGRK VAIDASMSIY QFLIAVRQGG DVLQNEEGET TSHLMGMFYR TIRMMENGIK PVYVFDGKPP QLKSGELAKR SERRAEAEKQ LQQAQAAGAE QEVEKFTKRL VKVTKQHNDE CKHLLSLMGI PYLDAPSEAE ASCAALVKAG KVYAAATEDM DCLTFGSPVL MRHLTASEAK KLPIQEFHLS RILQELGLNQ EQFVDLCILL GS
Citations	Hakoyama T., et al. (2009) Nature. 462(7272):514-7. Lal A., et al. (2009) Mol Cell. 35(5):610-25.
NCBI	NP_004102.1
ECLASS 10.1	32160409
ECLASS 11.0	32160409
UNSPSC	12352202
Alias	Flap structure-specific endonuclease 1,FEN-1,MF1,RAD2,Flap structure-specific endonuclease 1 DNase IV,Flap endonuclease 1,Flap structure specific endonuclease 1,hFEN1,Maturation factor 1
Similar products	FEN1, FEN-1, MF1, RAD2, Flap endonuclease 1, hFEN1, Maturation factor 1, Flap structure-specific endonuclease 1, Flap structure specific endonuclease 1, Flap structure-specific endonuclease 1 DNase IV, ATGP0442-10ug, ATGP0442-20ug, ATGP0442-50ug, ATGP0442-100ug, ATGP0442-250ug, ATGP0442-500ug, ATGP0442-1mg, ATGP0442-10, ATGP0442-20, ATGP0442-50, ATGP0442-100, ATGP0442-250, ATGP0442-500, ATGP0442-1
Available
Manufacturer - Type	Recombinant Protein
Storage Conditions	Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
Molecular Weight	42.5 kDa (380aa) confirmed by MALDI-TOF
Description	FEN-1, also known as Flap structure-specific endonuclease 1, removes 5' overhanging flaps in DNA repair and processes the 5' ends of Okazaki fragments in lagging strand DNA synthesis. The protein is a member of the XPG/RAD2 endonuclease family and is one of ten proteins essential for cell-free DNA replication. FEN-1 is highly homologous to yeast Rad2. The C-terminal region of FEN-1 may bind to PCNA, thus allowing FEN-1 to function as an exonuclease in DNA replication. Recombinant human FEN-1 protein was expressed in E. coli and purified by using conventional chromatography techniques.
Concentration	1mg/ml (determined by Bradford assay)
Formulation	Liquid in. 20mM Tris-HCl buffer (pH 8.0) containing 1mM DTT 10% glycerol
Antigen Species	Human
Gene Category	Enzymes & Proteases
Domain	1-380aa
Species of Protein	Human
Manufacturer - Search Terms	FEN1, Flap structure-specific endonuclease 1, FEN-1, MF1, RAD2, Flap structure-specific endonuclease 1 DNase IV, Flap endonuclease 1, Flap structure specific endonuclease 1, hFEN1, Maturation factor 1, ATGP0442-10ug, ATGP0442-20ug, ATGP0442-50ug, ATGP0442-100ug, ATGP0442-250ug, ATGP0442-500ug, ATGP0442-1mg, ATGP0442-10, ATGP0442-20, ATGP0442-50, ATGP0442-100, ATGP0442-250, ATGP0442-500, ATGP0442-1

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 500 ug

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Delivery expected until 7/31/2025

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