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Recombinant human RhoGDI 1/ARHGDIA protein

ArtNr NKM-ATGP0775-500ug
Hersteller NKMAX
Menge 500 ug
Quantity options 100 ug 20 ug 500 ug
Kategorie
Typ Proteins Recombinant
Format Liquid
Applikationen SDS-PAGE
Specific against Human (Homo sapiens)
Host E.coli
Konjugat/Tag HIS
Purity > 95% by SDS-PAGE
Sequence <MGSSHHHHHH SSGLVPRGSH> MSVNYKPPAQ KSIQEIQELD KDDESLRKYK EALLGRVAVS ADPNVPNVVV TGLTLVCSSA PGPLELDLTG DLESFKKQSF VLKEGVEYRI KISFRVNREI VSGMKYIQHT YRKGVKIDKT DYMVGSYGPR AEEYEFLTPV EEAPKGMLAR GSYSIKSRFT DDDKTDHLSW EWNLTIKKDW KD
Citations DerMardirossian C., et al. (2006) Mol Biol Cell. 17:4760-4768.
Leffers H., et al. (1993) Exp Cell Res. 209:165-174.
NCBI NP_004300
ECLASS 10.1 32160409
ECLASS 11.0 32160409
UNSPSC 12352202
Alias Rho GDP-dissociation inhibitor 1,GDIA1,RHOGDI,RHOGDI-1,Rho-GDI alpha
Similar products ARHGDIA, GDIA1, RHOGDI, RHOGDI-1, Rho GDP-dissociation inhibitor 1, Rho-GDI alpha, ATGP0775-10ug, ATGP0775-20ug, ATGP0775-50ug, ATGP0775-100ug, ATGP0775-250ug, ATGP0775-500ug, ATGP0775-1mg, ATGP0775-10, ATGP0775-20, ATGP0775-50, ATGP0775-100, ATGP0775-250, ATGP0775-500, ATGP0775-1
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Manufacturer - Type
Recombinant Protein
Storage Conditions
Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
Molecular Weight
22.9 kDa (202aa) confirmed by MALDI-TOF
Description
Rho GDP-dissociation inhibitor 1, also known ARHGDIA, belong to the RAS gene superfamily encoding small guanine nucleotide exchange (GTP/GDP) factors. Localized to the cytoplasm, ARHGDIA inhibits the dissociation of GDP from Rho proteins, thereby preventing GTP from binding to and subsequently activating Rho proteins. In humans ARHGDIA can be phosphorylated at Ser 101 by p21-activated kinase, an event that inhibits ARHGDIA activity and may result in positive feedback regulation of certain ARHGDIA target proteins. Recombinant human ARHGDIA protein, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography techniques.
Concentration
1mg/ml (determined by Bradford assay)
Formulation
Liquid in. 20mM Tris-HCl buffer (pH 8.0) containing 1mM DTT, 10% glycerol
Antigen Species
Human
Gene Category
Signal Transduction
Domain
24-204aa
Species of Protein
Human
Manufacturer - Search Terms
ARHGDIA, Rho GDP-dissociation inhibitor 1, GDIA1, RHOGDI, RHOGDI-1, Rho-GDI alpha, ATGP0775-10ug, ATGP0775-20ug, ATGP0775-50ug, ATGP0775-100ug, ATGP0775-250ug, ATGP0775-500ug, ATGP0775-1mg, ATGP0775-10, ATGP0775-20, ATGP0775-50, ATGP0775-100, ATGP0775-250, ATGP0775-500, ATGP0775-1

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

Menge: 500 ug
Lieferbar: In stock
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