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Recombinant human Glutathione Reductase protein

ArtNr NKM-ATGP1318-10ug
Hersteller NKMAX
Menge 10 ug
Quantity options 10 ug 250 ug 50 ug
Kategorie
Typ Proteins Recombinant
Format Liquid
Applikationen SDS-PAGE
Specific against Human (Homo sapiens)
Host E.coli
Konjugat/Tag HIS
Purity > 95% by SDS-PAGE
Sequence MGSSHHHHHH SSGLVPRGSH MGSMAMACRQ EPQPQGPPPA AGAVASYDYL VIGGGSGGLA SARRAAELGA RAAVVESHKL GGTCVNVGCV PKKVMWNTAV HSEFMHDHAD YGFPSCEGKF NWRVIKEKRD AYVSRLNAIY QNNLTKSHIE IIRGHAAFTS DPKPTIEVSG KKYTAPHILI ATGGMPSTPH ESQIPGASLG ITSDGFFQLE ELPGRSVIVG AGYIAVEMAG IL
Citations Stoll V S., et al. (1997) Biochemistry. 36:6437-6447.
Karplus P A., et al. (1987) J Mol biol. 195:701-729.
NCBI NP_000628
ECLASS 10.1 32160409
ECLASS 11.0 32160409
UNSPSC 12352202
Alias Glutathione reductase,GLuR,GRD1
Similar products Glutathione Reductase, GRD1, Glutathione reductase, GLuR, ATGP1318-10ug, ATGP1318-20ug, ATGP1318-50ug, ATGP1318-100ug, ATGP1318-250ug, ATGP1318-500ug, ATGP1318-1mg, ATGP1318-10, ATGP1318-20, ATGP1318-50, ATGP1318-100, ATGP1318-250, ATGP1318-500, ATGP1318-1
Lieferbar
Manufacturer - Type
Recombinant Protein
Manufacturer - Applications
Enzyme Activity, SDS-PAGE
Storage Conditions
Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
Molecular Weight
54.3 kDa (504aa) confirmed by MALDI-TOF
Description
Glutathione reductase, also known as GSR, is a member of the class-I pyridine nucleotide-disulfide oxidoreductase family. This enzyme is a homodimeric flavoprotein and plays a role in maintaining glutathione (GSH) in its reduced form by catalyzing the reduction of glutathione disulfide (GSSG) : GSSG + NADPH + H+ ->2GSH + NADP+. In most eukaryotic cells, GSR maintains the ratio of [GSH] / [GSSG], and participates in several vital functions such as the detoxification of reactive oxygen species as well as protein and DNA biosynthesis. Recombinant human GSR protein, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography techniques.
Concentration
1mg/ml (determined by Bradford assay)
Formulation
Liquid in. 20mM Tris-HCl buffer (pH 8.0) containing 1mM DTT, 10% glycerol, 0.1M NaCl
Antigen Species
Human
Gene Category
Redox Proteins
Domain
43-522aa
Bioactivity Comment Only
Specific activity is > 45unit/mg. The unit definition for glutathione reductase activity may be expressed in terms of the oxidation of NADPH or the reduction of GSSG since their molar ratio is 1:1. One unit of glutathione reductase oxidizes 1 umol of NADPH per minute at 37C, pH 7.5.
Species of Protein
Human
Manufacturer - Search Terms
Glutathione Reductase, Glutathione reductase, GLuR, GRD1, ATGP1318-10ug, ATGP1318-20ug, ATGP1318-50ug, ATGP1318-100ug, ATGP1318-250ug, ATGP1318-500ug, ATGP1318-1mg, ATGP1318-10, ATGP1318-20, ATGP1318-50, ATGP1318-100, ATGP1318-250, ATGP1318-500, ATGP1318-1

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

Menge: 10 ug
Lieferbar: In stock
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