Comparison

Recombinant human Glutathione Reductase protein

Item no. NKM-ATGP1318-10ug
Manufacturer NKMAX
Amount 10 ug
Quantity options 10 ug 250 ug 50 ug
Category
Type Proteins Recombinant
Format Liquid
Applications SDS-PAGE
Specific against Human (Homo sapiens)
Host E.coli
Conjugate/Tag HIS
Purity > 95% by SDS-PAGE
Sequence MGSSHHHHHH SSGLVPRGSH MGSMAMACRQ EPQPQGPPPA AGAVASYDYL VIGGGSGGLA SARRAAELGA RAAVVESHKL GGTCVNVGCV PKKVMWNTAV HSEFMHDHAD YGFPSCEGKF NWRVIKEKRD AYVSRLNAIY QNNLTKSHIE IIRGHAAFTS DPKPTIEVSG KKYTAPHILI ATGGMPSTPH ESQIPGASLG ITSDGFFQLE ELPGRSVIVG AGYIAVEMAG IL
Citations Stoll V S., et al. (1997) Biochemistry. 36:6437-6447.
Karplus P A., et al. (1987) J Mol biol. 195:701-729.
NCBI NP_000628
ECLASS 10.1 32160409
ECLASS 11.0 32160409
UNSPSC 12352202
Alias Glutathione reductase,GLuR,GRD1
Similar products Glutathione Reductase, GRD1, Glutathione reductase, GLuR, ATGP1318-10ug, ATGP1318-20ug, ATGP1318-50ug, ATGP1318-100ug, ATGP1318-250ug, ATGP1318-500ug, ATGP1318-1mg, ATGP1318-10, ATGP1318-20, ATGP1318-50, ATGP1318-100, ATGP1318-250, ATGP1318-500, ATGP1318-1
Available
Manufacturer - Type
Recombinant Protein
Manufacturer - Applications
Enzyme Activity, SDS-PAGE
Storage Conditions
Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
Molecular Weight
54.3 kDa (504aa) confirmed by MALDI-TOF
Description
Glutathione reductase, also known as GSR, is a member of the class-I pyridine nucleotide-disulfide oxidoreductase family. This enzyme is a homodimeric flavoprotein and plays a role in maintaining glutathione (GSH) in its reduced form by catalyzing the reduction of glutathione disulfide (GSSG) : GSSG + NADPH + H+ ->2GSH + NADP+. In most eukaryotic cells, GSR maintains the ratio of [GSH] / [GSSG], and participates in several vital functions such as the detoxification of reactive oxygen species as well as protein and DNA biosynthesis. Recombinant human GSR protein, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography techniques.
Concentration
1mg/ml (determined by Bradford assay)
Formulation
Liquid in. 20mM Tris-HCl buffer (pH 8.0) containing 1mM DTT, 10% glycerol, 0.1M NaCl
Antigen Species
Human
Gene Category
Redox Proteins
Domain
43-522aa
Bioactivity Comment Only
Specific activity is > 45unit/mg. The unit definition for glutathione reductase activity may be expressed in terms of the oxidation of NADPH or the reduction of GSSG since their molar ratio is 1:1. One unit of glutathione reductase oxidizes 1 umol of NADPH per minute at 37C, pH 7.5.
Species of Protein
Human
Manufacturer - Search Terms
Glutathione Reductase, Glutathione reductase, GLuR, GRD1, ATGP1318-10ug, ATGP1318-20ug, ATGP1318-50ug, ATGP1318-100ug, ATGP1318-250ug, ATGP1318-500ug, ATGP1318-1mg, ATGP1318-10, ATGP1318-20, ATGP1318-50, ATGP1318-100, ATGP1318-250, ATGP1318-500, ATGP1318-1

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

Amount: 10 ug
Available: In stock
available

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