Vergleich

Recombinant human DEDD protein

ArtNr NKM-ATGP1945-500ug
Hersteller NKMAX
Menge 500 ug
Quantity options 100 ug 10 ug 20 ug 250 ug 500 ug 50 ug
Kategorie
Typ Proteins
Format Liquid
Applikationen SDS-PAGE
Specific against Human (Homo sapiens)
Host E.coli
Konjugat/Tag HIS
Purity > 85% by SDS-PAGE
Sequence <MGSSHHHHHH SSGLVPRGSH> MAGLKRRASQ VWPEEHGEQE HGLYSLHRMF DIVGTHLTHR DVRVLSFLFV DVIDDHERGL IRNGRDFLLA LERQGRCDES NFRQVLQLLR IITRHDLLPY VTLKRRRAVC PDLVDKYLEE TSIRYVTPRA LSDPEPRPPQ PSKTVPPHYP VVCCPTSGPQ MCSKRPARGR ATLGSQRKRR KSVTPDPKEK QTCDIRLRVR AEYCQHETAL
Citations Stegh A H., et al. (1998) EMBO J. 17:5974-5986.
Schickling O., et al. (2001) Cell Death Differ. 8:1157-1168.
NCBI NP_127491
ECLASS 10.1 32160409
ECLASS 11.0 32160409
UNSPSC 12352202
Alias Death effector domain-containing protein,CASP8IP1,DEDD1,DEFT,FLDED1,KE05
Similar products DEDD, DEFT, Death effector domain-containing protein, CASP8IP1, DEDD1, FLDED1, KE05, ATGP1945-10ug, ATGP1945-20ug, ATGP1945-50ug, ATGP1945-100ug, ATGP1945-250ug, ATGP1945-500ug, ATGP1945-1mg, ATGP1945-10, ATGP1945-20, ATGP1945-50, ATGP1945-100, ATGP1945-250, ATGP1945-500, ATGP1945-1
Lieferbar
Manufacturer - Type
Recombinant Protein
Manufacturer - Applications
SDS-PAGE, Denatured
Storage Conditions
Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
Molecular Weight
38.9 kDa (338aa)
Description
Death effector domain-containing protein, also known as DEDD, is a cytoplasmic protein. It translocates to the nucleus during CD95-mediated apoptosis, where it localizes to nucleoli-like structures, activates caspase-6 and specifically inhibits RNA polymerase I-dependent transcription. The cell death activity of DEDD relates to its nuclear localization. DEDD is widely expressed in a variety of tissues, with highest levels in the testis. Overexpression of this gene was shown to induce weak apoptosis. Recombinant human DEDD protein, fused to His-tag at N-terminus, was expressed in E. coli.
Concentration
0.5mg/ml (determined by Bradford assay)
Formulation
Liquid in. 20mM Tris-HCl buffer (pH 8.0) containing 0.4M urea, 10% glycerol
Antigen Species
Human
Gene Category
Apoptosis
Domain
1-318aa
Species of Protein
Human
Manufacturer - Search Terms
DEDD, Death effector domain-containing protein, CASP8IP1, DEDD1, DEFT, FLDED1, KE05, ATGP1945-10ug, ATGP1945-20ug, ATGP1945-50ug, ATGP1945-100ug, ATGP1945-250ug, ATGP1945-500ug, ATGP1945-1mg, ATGP1945-10, ATGP1945-20, ATGP1945-50, ATGP1945-100, ATGP1945-250, ATGP1945-500, ATGP1945-1

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

Menge: 500 ug
Lieferbar: In stock
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