Comparison

Recombinant human DEDD protein

Item no. NKM-ATGP1945-500ug
Manufacturer NKMAX
Amount 500 ug
Quantity options 100 ug 10 ug 20 ug 250 ug 500 ug 50 ug
Category
Type Proteins
Format Liquid
Applications SDS-PAGE
Specific against Human (Homo sapiens)
Host E.coli
Conjugate/Tag HIS
Purity > 85% by SDS-PAGE
Sequence <MGSSHHHHHH SSGLVPRGSH> MAGLKRRASQ VWPEEHGEQE HGLYSLHRMF DIVGTHLTHR DVRVLSFLFV DVIDDHERGL IRNGRDFLLA LERQGRCDES NFRQVLQLLR IITRHDLLPY VTLKRRRAVC PDLVDKYLEE TSIRYVTPRA LSDPEPRPPQ PSKTVPPHYP VVCCPTSGPQ MCSKRPARGR ATLGSQRKRR KSVTPDPKEK QTCDIRLRVR AEYCQHETAL
Citations Stegh A H., et al. (1998) EMBO J. 17:5974-5986.
Schickling O., et al. (2001) Cell Death Differ. 8:1157-1168.
NCBI NP_127491
ECLASS 10.1 32160409
ECLASS 11.0 32160409
UNSPSC 12352202
Alias Death effector domain-containing protein,CASP8IP1,DEDD1,DEFT,FLDED1,KE05
Similar products DEDD, DEFT, Death effector domain-containing protein, CASP8IP1, DEDD1, FLDED1, KE05, ATGP1945-10ug, ATGP1945-20ug, ATGP1945-50ug, ATGP1945-100ug, ATGP1945-250ug, ATGP1945-500ug, ATGP1945-1mg, ATGP1945-10, ATGP1945-20, ATGP1945-50, ATGP1945-100, ATGP1945-250, ATGP1945-500, ATGP1945-1
Available
Manufacturer - Type
Recombinant Protein
Manufacturer - Applications
SDS-PAGE, Denatured
Storage Conditions
Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
Molecular Weight
38.9 kDa (338aa)
Description
Death effector domain-containing protein, also known as DEDD, is a cytoplasmic protein. It translocates to the nucleus during CD95-mediated apoptosis, where it localizes to nucleoli-like structures, activates caspase-6 and specifically inhibits RNA polymerase I-dependent transcription. The cell death activity of DEDD relates to its nuclear localization. DEDD is widely expressed in a variety of tissues, with highest levels in the testis. Overexpression of this gene was shown to induce weak apoptosis. Recombinant human DEDD protein, fused to His-tag at N-terminus, was expressed in E. coli.
Concentration
0.5mg/ml (determined by Bradford assay)
Formulation
Liquid in. 20mM Tris-HCl buffer (pH 8.0) containing 0.4M urea, 10% glycerol
Antigen Species
Human
Gene Category
Apoptosis
Domain
1-318aa
Species of Protein
Human
Manufacturer - Search Terms
DEDD, Death effector domain-containing protein, CASP8IP1, DEDD1, DEFT, FLDED1, KE05, ATGP1945-10ug, ATGP1945-20ug, ATGP1945-50ug, ATGP1945-100ug, ATGP1945-250ug, ATGP1945-500ug, ATGP1945-1mg, ATGP1945-10, ATGP1945-20, ATGP1945-50, ATGP1945-100, ATGP1945-250, ATGP1945-500, ATGP1945-1

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

Amount: 500 ug
Available: In stock
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