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Recombinant human ICAM-3/CD50 protein

ArtNr NKM-ATGP3931-100ug
Hersteller NKMAX
Menge 100 ug
Quantity options 100 ug 10 ug 20 ug 250 ug 500 ug 50 ug
Kategorie
Typ Proteins Recombinant
Format Liquid
Applikationen SDS-PAGE
Specific against Human (Homo sapiens)
Host Baculovirus-Infected Insect Cells
Konjugat/Tag HIS
Purity > 90% by SDS-PAGE
Sequence <ADL>QEFLLRV EPQNPVLSAG GSLFVNCSTD CPSSEKIALE TSLSKELVAS GMGWAAFNLS NVTGNSRILC SVYCNGSQIT GSSNITVYRL PERVELAPLP PWQPVGQNFT LRCQVEDGSP RTSLTVVLLR WEEELSRQPA VEEPAEVTAT VLASRDDHGA PFSCRTELDM QPQGLGLFVN TSAPRQLRTF VLPVTPPRLV APRFLEVETS WPVDCTLDGL FPASEAQVYL
Citations de Fougerolles AR., et al, (1992) J Exp Med. 175:185-190.
Serrador JM., et al, (1997) J Cell Biol. 138:1409-1423.
NCBI NP_002153.2
ECLASS 10.1 32160409
ECLASS 11.0 32160409
UNSPSC 12352202
Alias ICAM3,Intercellular adhesion molecule 3,ICAM-3,CD50,CDW50,ICAM-R,intercellular adhesion molecule 3 isoform 1
Similar products ICAM3, CD50, ATGP3931-10ug, ATGP3931-20ug, ATGP3931-50ug, ATGP3931-100ug, ATGP3931-250ug, ATGP3931-500ug, ATGP3931-1mg, ATGP3931-10, ATGP3931-20, ATGP3931-50, ATGP3931-100, ATGP3931-250, ATGP3931-500, ATGP3931-1
Lieferbar
Manufacturer - Type
Recombinant Protein
Manufacturer - Applications
SDS-PAGE, Bioactivity
Manufacturer - Conjugate / Tag
hIgG-His-Tag
Manufacturer - Host
Baculovirus
Storage Conditions
Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
Molecular Weight
76.7 kDa (698aa)
Description
ICAM-3/CD50, also known as CD50 (Cluster of Differentiation 50), is a member of the intercellular adhesion molecule (ICAM) family. All ICAM proteins are type I transmembrane glycoproteins, contain 2-9 immunoglobulin-like C2-type domains, and bind to the leukocyte adhesion LFA-1 protein. This protein is constitutively and abundantly expressed by all leukocytes and may be the most important ligand for LFA-1 in the initiation of the immune response. It functions not only as an adhesion molecule, but also as a potent signaling molecule. Recombinant human ICAM-3/CD50, fused hIgG-His-tag at C-terminus, was expressed in insect cell and purified by using conventional chromatography techniques.
Concentration
0.25mg/ml (determined by Bradford assay)
Formulation
Liquid in. Phosphate-Buffered Saline (pH 7.4) containing 10% glycerol
Antigen Species
Human
Gene Category
Signal Transduction
Domain
30-485aa
Endotoxin
< 1 EU per 1ug of protein (determined by LAL method)
Bioactivity Comment Only
Measured by the ability of the immobilized protein to support the adhesion of HL-60 human promyelocytic cells. When cells are added to Human ICAM-3/CD50 coated plates, the ED50 range ≤4ug/ml.
Predicted nterm
Ala
Species of Protein
Human
Manufacturer - Search Terms
ICAM3, CD50, ATGP3931-10ug, ATGP3931-20ug, ATGP3931-50ug, ATGP3931-100ug, ATGP3931-250ug, ATGP3931-500ug, ATGP3931-1mg, ATGP3931-10, ATGP3931-20, ATGP3931-50, ATGP3931-100, ATGP3931-250, ATGP3931-500, ATGP3931-1

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

Menge: 100 ug
Lieferbar: In stock
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