Comparison

Recombinant human ICAM-3/CD50 protein

Item no. NKM-ATGP3931-100ug
Manufacturer NKMAX
Amount 100 ug
Quantity options 100 ug 10 ug 20 ug 250 ug 500 ug 50 ug
Category
Type Proteins Recombinant
Format Liquid
Applications SDS-PAGE
Specific against Human (Homo sapiens)
Host Baculovirus-Infected Insect Cells
Conjugate/Tag HIS
Purity > 90% by SDS-PAGE
Sequence <ADL>QEFLLRV EPQNPVLSAG GSLFVNCSTD CPSSEKIALE TSLSKELVAS GMGWAAFNLS NVTGNSRILC SVYCNGSQIT GSSNITVYRL PERVELAPLP PWQPVGQNFT LRCQVEDGSP RTSLTVVLLR WEEELSRQPA VEEPAEVTAT VLASRDDHGA PFSCRTELDM QPQGLGLFVN TSAPRQLRTF VLPVTPPRLV APRFLEVETS WPVDCTLDGL FPASEAQVYL
Citations de Fougerolles AR., et al, (1992) J Exp Med. 175:185-190.
Serrador JM., et al, (1997) J Cell Biol. 138:1409-1423.
NCBI NP_002153.2
ECLASS 10.1 32160409
ECLASS 11.0 32160409
UNSPSC 12352202
Alias ICAM3,Intercellular adhesion molecule 3,ICAM-3,CD50,CDW50,ICAM-R,intercellular adhesion molecule 3 isoform 1
Similar products ICAM3, CD50, ATGP3931-10ug, ATGP3931-20ug, ATGP3931-50ug, ATGP3931-100ug, ATGP3931-250ug, ATGP3931-500ug, ATGP3931-1mg, ATGP3931-10, ATGP3931-20, ATGP3931-50, ATGP3931-100, ATGP3931-250, ATGP3931-500, ATGP3931-1
Available
Manufacturer - Type
Recombinant Protein
Manufacturer - Applications
SDS-PAGE, Bioactivity
Manufacturer - Conjugate / Tag
hIgG-His-Tag
Manufacturer - Host
Baculovirus
Storage Conditions
Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
Molecular Weight
76.7 kDa (698aa)
Description
ICAM-3/CD50, also known as CD50 (Cluster of Differentiation 50), is a member of the intercellular adhesion molecule (ICAM) family. All ICAM proteins are type I transmembrane glycoproteins, contain 2-9 immunoglobulin-like C2-type domains, and bind to the leukocyte adhesion LFA-1 protein. This protein is constitutively and abundantly expressed by all leukocytes and may be the most important ligand for LFA-1 in the initiation of the immune response. It functions not only as an adhesion molecule, but also as a potent signaling molecule. Recombinant human ICAM-3/CD50, fused hIgG-His-tag at C-terminus, was expressed in insect cell and purified by using conventional chromatography techniques.
Concentration
0.25mg/ml (determined by Bradford assay)
Formulation
Liquid in. Phosphate-Buffered Saline (pH 7.4) containing 10% glycerol
Antigen Species
Human
Gene Category
Signal Transduction
Domain
30-485aa
Endotoxin
< 1 EU per 1ug of protein (determined by LAL method)
Bioactivity Comment Only
Measured by the ability of the immobilized protein to support the adhesion of HL-60 human promyelocytic cells. When cells are added to Human ICAM-3/CD50 coated plates, the ED50 range ≤4ug/ml.
Predicted nterm
Ala
Species of Protein
Human
Manufacturer - Search Terms
ICAM3, CD50, ATGP3931-10ug, ATGP3931-20ug, ATGP3931-50ug, ATGP3931-100ug, ATGP3931-250ug, ATGP3931-500ug, ATGP3931-1mg, ATGP3931-10, ATGP3931-20, ATGP3931-50, ATGP3931-100, ATGP3931-250, ATGP3931-500, ATGP3931-1

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

Amount: 100 ug
Available: In stock
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