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Recombinant human PDH kinase 1/PDK1 protein

ArtNr NKM-PDK0904-20ug
Hersteller NKMAX
Menge 20 ug
Quantity options 100 ug 20 ug 500 ug
Kategorie
Typ Proteins Recombinant
Format Liquid
Applikationen SDS-PAGE
Specific against Human (Homo sapiens)
Host E.coli
Konjugat/Tag HIS
Purity > 95% by SDS-PAGE
Sequence MGSSHHHHHH SSGLVPRGSH MSSDSGSSPA SERGVPGQVD FYARFSPSPL SMKQFLDFGS VNACEKTSFM FLRQELPVRL ANIMKEISLL PDNLLRTPSV QLVQSWYIQS LQELLDFKDK SAEDAKAIYD FTDTVIRIRN RHNDVIPTMA QGVIEYKESF GVDPVTSQNV QYFLDRFYMS RISIRMLLNQ HSLLFGGKGK GSPSHRKHIG SINPNCNVLE VIKDGYENAR RL
Citations Gudi R ., et al. (1995). J Biol chem. 270(48) : 28989-94
Xie Z., et al. (2006). BMC Cancer. 6 :77
NCBI NP_002601
ECLASS 10.1 32160409
ECLASS 11.0 32160409
UNSPSC 12352202
Alias Pyruvate dehydrogenase kinase 1,Pyruvate dehydrogenase kinase,PDHK1,Isozyme 1,Isoenzyme
Similar products PDK1, PDHK1, Pyruvate dehydrogenase kinase isoform 1, PDK 1, Pyruvate dehydrogenase kinase, Isozyme 1, Pyruvate dehydrogenase kinase isozyme 1, Pyruvate dehydrogenase kinase 1, PDHK 1, Mitochondrial pyruvate dehydrogenase kinase isoenzyme1, Isozyme1, Isozyme 1 HGNC:8809, Isoenzyme1, Isoenzyme 1, PDK0904-10ug, PDK0904-20ug, PDK0904-50ug, PDK0904-100ug, PDK0904-250ug, PDK0904-500ug, PDK0904-1mg, PDK0904-010, PDK0904-020, PDK0904-050, PDK0904-100, PDK0904-250, PDK0904-500, PDK0904-01M
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Manufacturer - Type
Recombinant Protein
Storage Conditions
Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
Molecular Weight
48.6 kDa (429aa)
Description
PDK1 (pyruvate dehydrogenase kinase isoform 1) is involved in the regulation of enzymatic activity of mammalian pyruvate dehydrogenase (PDH) that is a part of a mitochondrial multienzyme complex to catalyze the oxidative decarboxylation of pyruvate and is one of the major enzymes responsible for the regulation of homeostasis of carbohydrate fuels in mammals. PDK1 has been found to serve as an effective therapeutic target for inhibition of glioblastoma growth. Recombinant human PDK1 protein, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography techniques.
Concentration
0.5mg/ml (determined by Bradford assay)
Formulation
Liquid in. 20mM Tris-HCl buffer (pH 7.0) containing 100mM NaCl, 0.5mM DTT, 0.1mM EDTA, 0.1mM PMSF, 1mM MgCl2, 40% glycerol
Antigen Species
Human
Gene Category
Enzymes & Proteases
Domain
29-436aa
Species of Protein
Human
Manufacturer - Search Terms
Pyruvate dehydrogenase kinase isozyme 1, Pyruvate dehydrogenase kinase isoform 1, Pyruvate dehydrogenase kinase 1, Pyruvate dehydrogenase kinase, PDK1, PDK 1, PDHK1, PDHK 1, Mitochondrial pyruvate dehydrogenase kinase isoenzyme1, Isozyme1, Isozyme 1 HGNC:8809, Isozyme 1, Isoenzyme1, Isoenzyme 1, PDK0904-10ug, PDK0904-20ug, PDK0904-50ug, PDK0904-100ug, PDK0904-250ug, PDK0904-500ug, PDK0904-1mg, PDK0904-010, PDK0904-020, PDK0904-050, PDK0904-100, PDK0904-250, PDK0904-500, PDK0904-01M

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

Menge: 20 ug
Lieferbar: In stock
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