[Novoprotein] Recombinant Mouse Nerve Growth Factor Receptor/NGFR/TNFRSF16/CX271 (C-Fc)

Lyophilized protein should be stored at < -20C, though stable at room temperature for 3 weeks.
Reconstituted protein solution can be stored at 4-7C for 2-7 days.
Aliquots of reconstituted samples are stable at < -20C for 3 months.

Recombinant Mouse Nerve Growth Factor Receptor is produced by our Mammalian expression system & the target gene encoding Gly20-Asn243 is expressed with a Fc tag at the C-terminus.

Mouse Tumor necrosis factor receptor superfamily member 16(TNFRSF16) is a single-pass type I membrane protein which contains 1 death domain & 4 TNFR-Cys repeats. It has low affinity receptor which can bind to NGF, BDNF, NT-3, & NT-4. It can mediate cell survival as well as cell death of neural cells. TNFRSF16 plays a role in the regulation of the translocation of GLUT4 to the cell surface in adipocytes & skeletal muscle cells in response to insulin, probably by regulating RAB31 activity, & thereby contributes to the regulation of insulin-dependent glucose uptake. It binds to rabies virus glycoprotein Gs. Necessary for the circadian oscilllation of the clock genes ARNTL/BMAL1, PER1, PER2 & NR1D1 in the suprachiasmatic nucleus (SCN) of the brain & in liver & of the genes involved in glucose & lipid metabolism in the liver.

Always centrifuge tubes before opening. Do not mix by vortex or pipetting.
It is not recommended to reconstitute to a concentration less than 100 ug/ml.
Dissolve the lyophilized protein in ddH2O.
Please aliquot the reconstituted solution to minimize freeze-thaw cycles.