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IL-10 Recombinant Protein

ArtNr PRS-40-253-0.01mg
Hersteller ProSci
Menge 0.01 mg
Quantity options 0.002 mg 0.01 mg
Kategorie
Typ Proteins Recombinant
Format Lyophilized
Specific against other
Purity Greater than 98% by SDS-PAGE gel and HPLC analyses.<br><br>Endotoxin level is less than 0.1 ng per μg (1EU/μg).
Sequence MSPGQGTQSE NSCTHFPGNL PNMLRDLRDA FSRVKTFFQM KDQLDNLLLK ESLLEDFKGY LGCQALSEMI QFYLEEVMPQ AENQDPDIKA HVNSLGENLK TLRLRLRRCH RFLPCENKSK AVEQVKNAFN KLQEKGIYKA MSEFDIFINY IEAYMTMKIR N
NCBI IL10
ECLASS 10.1 32160409
ECLASS 11.0 32160409
UNSPSC 12352202
Alias CSIF,TGIF,GVHDS,IL-10,IL10A,Interleukin-10,Cytokine synthesis inhibitory factor
Versandbedingung Raumtemperatur
Lieferbar
Manufacturer - Type
Recombinant Proteins
Shipping Temperature
Room Temp
Storage Conditions
The lyophilized IL-10 recombinant protein is stable for at least 2 years from date of receipt at -20˚ C. Reconstituted IL-10 is stable for at least 3 months when stored in working aliquots with a carrier protein at -20˚ C. As with any protein, exposing IL-10 recombinant protein to repeated freeze / thaw cycles is not recommended. When working with proteins care should be taken to keep recombinant protein at a cool and stable temperature.
Biological Activity
Biological activity was determined by the dose - dependent co - stimulation (with human IL - 4) of MC/9 cells. The ED50 was found to be ≤ 2.0 ng/mL, corresponding to a specific activity of ≥ 5 x 105 units/mg.
Background
IL-10 is an immunosuppressive cytokine produced by a variety of mammalian cell types including macrophages, monocytes, T cells, B cells and keratinocytes. IL-10 inhibits the expression of proinflammatory cytokines such as IL-1 and TNFα . Like IL-4, IL-10 enhances humoral immune responses and attenuates cell-mediated immune reactions. Human IL-10 active on murine cells, but murine IL-10 is inactive on human cells. Recombinant human IL-10 is an 18.6 kDa protein of 161 amino acid residues.
By Type
Cancer, Chemokines & Cytokines, Immunology, Infectious Disease, Innate Immunity, Neuroscience, Signal Transduction, Stem Cell
Protein Gi #
10835141
NCBI Official Name
interleukin 10
NCBI Organism
Homo sapiens
Disclaimer
This product is for research use only.
Manufacturer - Species
Human
By Species
Human

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

Menge: 0.01 mg
Lieferbar: In stock
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