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IL-10 Recombinant Protein

IL-10 Recombinant Protein

Item no.	PRS-40-253-0.01mg
Manufacturer	ProSci
Amount	0.01 mg
Quantity options	0.002 mg 0.01 mg
Category	Neuroscience Neuroinflammation Peptides & Proteins Recombinant Proteins Cell Biology Cell Culture Cytokines
Type	Proteins Recombinant
Format	Lyophilized
Specific against	other
Purity	Greater than 98% by SDS-PAGE gel and HPLC analyses.<br><br>Endotoxin level is less than 0.1 ng per μg (1EU/μg).
Sequence	MSPGQGTQSE NSCTHFPGNL PNMLRDLRDA FSRVKTFFQM KDQLDNLLLK ESLLEDFKGY LGCQALSEMI QFYLEEVMPQ AENQDPDIKA HVNSLGENLK TLRLRLRRCH RFLPCENKSK AVEQVKNAFN KLQEKGIYKA MSEFDIFINY IEAYMTMKIR N
NCBI	IL10
ECLASS 10.1	32160409
ECLASS 11.0	32160409
UNSPSC	12352202
Alias	CSIF,TGIF,GVHDS,IL-10,IL10A,Interleukin-10,Cytokine synthesis inhibitory factor
Shipping Condition	Room temperature
Available
Manufacturer - Type	Recombinant Proteins
Shipping Temperature	Room Temp
Storage Conditions	The lyophilized IL-10 recombinant protein is stable for at least 2 years from date of receipt at -20˚ C. Reconstituted IL-10 is stable for at least 3 months when stored in working aliquots with a carrier protein at -20˚ C. As with any protein, exposing IL-10 recombinant protein to repeated freeze / thaw cycles is not recommended. When working with proteins care should be taken to keep recombinant protein at a cool and stable temperature.
Biological Activity	Biological activity was determined by the dose - dependent co - stimulation (with human IL - 4) of MC/9 cells. The ED50 was found to be ≤ 2.0 ng/mL, corresponding to a specific activity of ≥ 5 x 10⁵ units/mg.
Background	IL-10 is an immunosuppressive cytokine produced by a variety of mammalian cell types including macrophages, monocytes, T cells, B cells and keratinocytes. IL-10 inhibits the expression of proinflammatory cytokines such as IL-1 and TNFα . Like IL-4, IL-10 enhances humoral immune responses and attenuates cell-mediated immune reactions. Human IL-10 active on murine cells, but murine IL-10 is inactive on human cells. Recombinant human IL-10 is an 18.6 kDa protein of 161 amino acid residues.
By Type	Cancer, Chemokines & Cytokines, Immunology, Infectious Disease, Innate Immunity, Neuroscience, Signal Transduction, Stem Cell
Protein Gi #	10835141
NCBI Official Name	interleukin 10
NCBI Organism	Homo sapiens
Disclaimer	This product is for research use only.
Manufacturer - Species	Human
By Species	Human

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 0.01 mg

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Delivery expected until 11/6/2025

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