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SARS-CoV-2 S1 protein (HV69-70del, Y144del, N501Y, A570D, D614G, P681H), Fc Tag

SARS-CoV-2 S1 protein (HV69-70del, Y144del, N501Y, A570D, D614G, P681H), Fc Tag

Hersteller	ACROBiosystems
Kategorie	Peptides & Proteins Recombinant Proteins
Typ	Proteins Recombinant
Specific against	other
Format	Powder
Menge	1mg
ArtNr	S1D-C5254-1mg
Konjugat/Tag	Fc
eClass 6.1	34160400
eClass 9.0	42020190
Lieferbar
Bioactivity Legend 1	Immobilized Human ACE2, His Tag (Cat. No. AC2-H52H8) at 2 ?g/mL (100 ?L/well) can bind SARS-CoV-2 S1 protein, Fc Tag (Cat. No. S1D-C5254) with a linear range of 0.4-6 ng/mL (QC tested).
Bioactivity Legend 2	Immobilized SARS-CoV-2 S1 protein, Fc Tag (Cat. No. S1D-C5254) at 2 ?g/mL (100 ?L/well) can bind Human ACE2, His Tag (Cat. No. AC2-H52H8) with a linear range of 0.078-0.156 ?g/mL (Routinely tested).
Buffer	50 mM Tris, 100 mM Glycine, 0.2 M Arginine, 150 mM NaCl, pH7.5
Characteristics	This protein carries a human IgG1 Fc tag at the C-terminus. The protein has a calculated MW of 101.1 kDa. The protein migrates as 125-150 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
Description	It's been reported that Coronavirus can infect the human respiratory epithelial cells through interaction with the human ACE2 receptor. The spike protein is a large type I transmembrane protein containing two subunits, S1 and S2. S1 mainly contains a receptor binding domain (RBD), which is responsible for recognizing the cell surface receptor. S2 contains basic elements needed for the membrane fusion.The S protein plays key parts in the induction of neutralizing-antibody and T-cell responses, as well as protective immunity.
Endotoxin Level	Less than 1.0 EU per ?g by the LAL method.
Exp Region	Val 16 - Arg 685
Expression System	HEK293
Molecular Weight	101.1 kDa
Molecule	S1 protein
SDS-PAGE Legend	SARS-CoV-2 S1 protein, Fc Tag on SDS-PAGE under reducing (R) condition. The gel was stained overnight with Coomassie Blue. The purity of the protein is greater than 95%.
Storage	-20?

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Menge: 1mg

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Lieferung vsl. bis 06.06.2024

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