ArtNr |
TSR-H525a-100ug |
Hersteller |
ACROBiosystems
|
Menge |
100 ug |
Quantity options |
100 ug
1 mg
|
Kategorie |
|
Typ |
Proteins Recombinant |
Format |
Solid |
Specific against |
Human (Homo sapiens) |
Host |
HEK293 |
Konjugat/Tag |
Unconjugated, Fc |
Purity |
95% |
Citations |
(1) Lucia Pattarini, et al., 2017, J Exp Med.214(5): 1529-1546. (2) Wang J., et al., 2008, Cell. Mol. Immunol. 5:99-106. (3) Soumelis V., et al., 2002, Nat. Immunol. 3:673-680. |
NCBI |
NP_071431.2 |
ECLASS 10.1 |
32160409 |
ECLASS 11.0 |
32160409 |
UNSPSC |
12352202 |
Alias |
TSLP R,CRLF2,IL-XR,ILXR,p2RY8/CRLF2 fusion,TSLP receptor,TSLPR,CRL2,CRLF2Y,Cytokine receptor-like 2 |
Versandbedingung |
Raumtemperatur |
Lieferbar |
|
Manufacturer - Category |
Protein / Other Recombinant Proteins |
Manufacturer - Conjugate / Tag |
C-Fc, Unconjugated |
Shipping Temperature |
RT |
Storage Conditions |
-20°C |
Molecular Weight |
50.4 kDa |
Description |
Human TSLP R, Fc Tag (TSR-H525a) is expressed from human 293 cells (HEK293). It contains AA Gly 25 - Lys 231 (Accession # Q9HC73-1). |
Background |
Receptor for thymic stromal lymphopoietin (TSLP). CRLF2 / TSLPR is a member of the type I cytokine receptor family. Together with the interleukin 7 receptor (IL7R) and TSLP activate STAT3, STAT5, and JAK2 pathways, which control processes such as cell proliferation and development of the hematopoietic system. |
Molecule |
TSLP R |
Exp Region |
Gly 25 - Lys 231 |
Characteristics |
This protein carries a human IgG1 Fc tag at the C-terminus. The protein has a calculated MW of 50.4 kDa. The protein migrates as 60-65 kDa when calibrated against Star Ribbon Pre-stained Protein Marker under reducing (R) condition (SDS-PAGE) due to glycosylation. |
Endotoxin |
1.0 EU per μg |
Buffer |
Tris with Glycine, Arginine and NaCl, pH7.5 |
Stability |
-20°C to -70°C for 12 months in lyophilized state; -70°C for 3 months under sterile conditions after reconstitution._x000D_For long term storage, the product should be stored at lyophilized state at -20°C or lower. |
Protectant |
trehalose |
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