Item no. |
TSR-H525a-100ug |
Manufacturer |
ACROBiosystems
|
Amount |
100 ug |
Quantity options |
100 ug
1 mg
|
Category |
|
Type |
Proteins Recombinant |
Format |
Solid |
Specific against |
Human (Homo sapiens) |
Host |
HEK293 |
Conjugate/Tag |
Unconjugated, Fc |
Purity |
95% |
Citations |
(1) Lucia Pattarini, et al., 2017, J Exp Med.214(5): 1529-1546. (2) Wang J., et al., 2008, Cell. Mol. Immunol. 5:99-106. (3) Soumelis V., et al., 2002, Nat. Immunol. 3:673-680. |
NCBI |
NP_071431.2 |
ECLASS 10.1 |
32160409 |
ECLASS 11.0 |
32160409 |
UNSPSC |
12352202 |
Alias |
TSLP R,CRLF2,IL-XR,ILXR,p2RY8/CRLF2 fusion,TSLP receptor,TSLPR,CRL2,CRLF2Y,Cytokine receptor-like 2 |
Shipping condition |
Room temperature |
Available |
|
Manufacturer - Category |
Protein / Other Recombinant Proteins |
Manufacturer - Conjugate / Tag |
C-Fc, Unconjugated |
Shipping Temperature |
RT |
Storage Conditions |
-20°C |
Molecular Weight |
50.4 kDa |
Description |
Human TSLP R, Fc Tag (TSR-H525a) is expressed from human 293 cells (HEK293). It contains AA Gly 25 - Lys 231 (Accession # Q9HC73-1). |
Background |
Receptor for thymic stromal lymphopoietin (TSLP). CRLF2 / TSLPR is a member of the type I cytokine receptor family. Together with the interleukin 7 receptor (IL7R) and TSLP activate STAT3, STAT5, and JAK2 pathways, which control processes such as cell proliferation and development of the hematopoietic system. |
Molecule |
TSLP R |
Exp Region |
Gly 25 - Lys 231 |
Characteristics |
This protein carries a human IgG1 Fc tag at the C-terminus. The protein has a calculated MW of 50.4 kDa. The protein migrates as 60-65 kDa when calibrated against Star Ribbon Pre-stained Protein Marker under reducing (R) condition (SDS-PAGE) due to glycosylation. |
Endotoxin |
1.0 EU per μg |
Buffer |
Tris with Glycine, Arginine and NaCl, pH7.5 |
Stability |
-20°C to -70°C for 12 months in lyophilized state; -70°C for 3 months under sterile conditions after reconstitution._x000D_For long term storage, the product should be stored at lyophilized state at -20°C or lower. |
Protectant |
trehalose |
Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.
All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.