LRP5 Antibody

ArtNr	PRS-13-045-100uL
Hersteller	ProSci
Menge	100 uL
Quantity options	100 uL
Kategorie	Oncology Neuroscience Metabolism Diabetes Glucose Homeostasis Cholesterol & Lipid Metabolism Neural Mitochondrial Function Targets for Rodent Neurosciences Antibodies By Cell Type Glioma Obesity Immunohistochemistry Western Blot Lipoprotein Receptors & Associated Proteins Primary Antibodies
Typ	Antibody Primary
Format	Liquid
Applikationen	WB, IHC
Specific against	Human (Homo sapiens), Mouse (Murine, Mus musculus), Rat (Rattus norvegicus)
Host	Rabbit
Isotype	IgG
Konjugat/Tag	Unconjugated
NCBI	LRP5
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Alias	LRP5,low density lipoprotein receptor-related protein 5,HGNC:6697,BMND1,HBM,LR3,LRP7,OPPG,OPS,VBCH2,low density lipoprotein receptor-related protein 7,osteoporosis pseudoglioma syndrome
Versandbedingung	Gekühlt
Lieferbar
Specificity	Human,Mouse,Rat
Manufacturer - Type	Primary Antibodies
Shipping Temperature	Blue Ice
Storage Conditions	Store at -20˚ C. Avoid freeze / thaw cycles.
Molecular Weight	Observed: 150kDa
Manufacturer - Research Area	Cancer, Cell Cycle, Neuroscience, Signal Transduction, Stem Cell
Background	This gene encodes a transmembrane low-density lipoprotein receptor that binds and internalizes ligands in the process of receptor-mediated endocytosis. This protein also acts as a co-receptor with Frizzled protein family members for transducing signals by Wnt proteins and was originally cloned on the basis of its association with type 1 diabetes mellitus in humans. This protein plays a key role in skeletal homeostasis and many bone density related diseases are caused by mutations in this gene. Mutations in this gene also cause familial exudative vitreoretinopathy. Alternative splicing results in multiple transcript variants.
By Type	Cancer, Cell Cycle, Neuroscience, Signal Transduction, Stem Cell
Modifications	None
Purification	Affinity purification
Positive Control 1	Mouse liver
Positive Control 2	Rat liver
Concentration	batch dependent
Buffer	PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Application Note	WB: 1:500 - 1:2000 IHC: 1:50 - 1:200
Immunogen	Recombinant fusion protein containing a sequence corresponding to amino acids 1000-1250 of human LRP5 (NP_002326.2).
Clonality	Polyclonal
NCBI Official Name	low density lipoprotein receptor-related protein 5
NCBI Organism	Homo sapiens
User Note	Optimal dilutions for each application to be determined by the researcher.

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Menge: 100 uL

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Lieferung vsl. bis 04.12.2025

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