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PARP1 Antibody, KO Validated

ArtNr PRS-13-327-100uL
Hersteller ProSci
Menge 100 uL
Quantity options 100 uL
Kategorie
Typ Antibody Primary
Format Liquid
Applikationen WB, IF, IP, IHC, CHIP
Specific against Human (Homo sapiens), Mouse (Murine, Mus musculus), Rat (Rattus norvegicus)
Host Rabbit
Isotype IgG
Konjugat/Tag Unconjugated
NCBI PARP1
ECLASS 10.1 32160702
ECLASS 11.0 32160702
UNSPSC 12352203
Alias KIF3B,PARP,PPOL,ADPRT,ARTD1,ADPRT1,PARP-1,ADPRT 1,pADPRT-1
Versandbedingung Gekühlt
Lieferbar
Specificity Human,Mouse,Rat
Manufacturer - Type
Primary Antibodies
Shipping Temperature
Blue Ice
Storage Conditions
Store at -20˚ C. Avoid freeze / thaw cycles.
Molecular Weight
Observed: 100kDa, 110kDa, 125kDa
Manufacturer - Research Area
Cell Cycle, Immunology, Signal Transduction
Background
This gene encodes a chromatin-associated enzyme, poly(ADP-ribosyl)transferase, which modifies various nuclear proteins by poly(ADP-ribosyl)ation. The modification is dependent on DNA and is involved in the regulation of various important cellular processes such as differentiation, proliferation, and tumor transformation and also in the regulation of the molecular events involved in the recovery of cell from DNA damage. In addition, this enzyme may be the site of mutation in Fanconi anemia, and may participate in the pathophysiology of type I diabetes.
By Type
Cell Cycle, Immunology, Signal Transduction
Badges
KO
Modifications
None
Purification
Affinity purification
Validation
Antibody is Knockout validated.
Positive Control 1
Jurkat
Positive Control 2
HeLa
Positive Control 3
RAW264.7
Positive Control 4
C6
Positive Control 5
Mouse testis
Positive Control 6
Mouse brain
Concentration
batch dependent
Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Application Note
WB: 1:1000 - 1:3000
IHC: 1:50 - 1:200
IF: 1:50 - 1:200
IP: 1:50 - 1:200
CHIP: 1:50 - 1:200
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 81-390 of human PARP1 (NP_001609.2).
Clonality
Polyclonal
NCBI Official Name
poly (ADP-ribose) polymerase 1
NCBI Organism
Homo sapiens
User Note
Optimal dilutions for each application to be determined by the researcher.
Validation
Antibody is Knockout validated.

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

Menge: 100 uL
Lieferbar: In stock
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