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PARP1 Antibody, KO Validated

PARP1 Antibody, KO Validated

Item no.	PRS-13-327-100uL
Manufacturer	ProSci
Amount	100 uL
Quantity options	100 uL
Category	Oncology Antibodies By Cell Type Carcinoma Hematology Lymphoma Melanoma Sarcoma Cell Biology Cytoskeleton Immunohistochemistry Immunoprecipitation Western Blot Immunofluorescence Primary Antibodies CHiP small GTPases Arf Subfamily
Type	Antibody Primary
Format	Liquid
Applications	WB, IF, IP, IHC, CHIP
Specific against	Human (Homo sapiens), Mouse (Murine, Mus musculus), Rat (Rattus norvegicus)
Host	Rabbit
Isotype	IgG
Conjugate/Tag	Unconjugated
NCBI	PARP1
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Alias	KIF3B,PARP,PPOL,ADPRT,ARTD1,ADPRT1,PARP-1,ADPRT 1,pADPRT-1
Shipping Condition	Cool pack
Available
Specificity	Human,Mouse,Rat
Manufacturer - Type	Primary Antibodies
Shipping Temperature	Blue Ice
Storage Conditions	Store at -20˚ C. Avoid freeze / thaw cycles.
Molecular Weight	Observed: 100kDa, 110kDa, 125kDa
Manufacturer - Research Area	Cell Cycle, Immunology, Signal Transduction
Background	This gene encodes a chromatin-associated enzyme, poly(ADP-ribosyl)transferase, which modifies various nuclear proteins by poly(ADP-ribosyl)ation. The modification is dependent on DNA and is involved in the regulation of various important cellular processes such as differentiation, proliferation, and tumor transformation and also in the regulation of the molecular events involved in the recovery of cell from DNA damage. In addition, this enzyme may be the site of mutation in Fanconi anemia, and may participate in the pathophysiology of type I diabetes.
By Type	Cell Cycle, Immunology, Signal Transduction
Badges	KO
Modifications	None
Purification	Affinity purification
Validation	Antibody is Knockout validated.
Positive Control 1	Jurkat
Positive Control 2	HeLa
Positive Control 3	RAW264.7
Positive Control 4	C6
Positive Control 5	Mouse testis
Positive Control 6	Mouse brain
Concentration	batch dependent
Buffer	PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Application Note	WB: 1:1000 - 1:3000 IHC: 1:50 - 1:200 IF: 1:50 - 1:200 IP: 1:50 - 1:200 CHIP: 1:50 - 1:200
Immunogen	Recombinant fusion protein containing a sequence corresponding to amino acids 81-390 of human PARP1 (NP_001609.2).
Clonality	Polyclonal
NCBI Official Name	poly (ADP-ribose) polymerase 1
NCBI Organism	Homo sapiens
User Note	Optimal dilutions for each application to be determined by the researcher.
Validation	Antibody is Knockout validated.

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 100 uL

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Delivery expected until 11/6/2025

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