COX6A1 Antibody

ArtNr	PRS-19-164-100uL
Hersteller	ProSci
Menge	100 uL
Quantity options	100 uL
Kategorie	Antibodies Cell Biology Cell Status Apoptosis Immunohistochemistry Western Blot Immunofluorescence Primary Antibodies
Typ	Antibody Primary
Format	Liquid
Applikationen	WB, IF, IHC
Specific against	Human (Homo sapiens), Mouse (Murine, Mus musculus), Rat (Rattus norvegicus)
Host	Rabbit
Isotype	IgG
Konjugat/Tag	Unconjugated
NCBI	COX6A1
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Alias	Cytochrome c oxidase subunit 6A1,mitochondrial,Cytochrome c oxidase polypeptide VIa-liver,Cytochrome c oxidase subunit VIA-liver,COX VIa-L,COX6A1,COX6AL
Versandbedingung	Gekühlt
Lieferbar
Specificity	Human,Mouse,Rat
Manufacturer - Type	Primary Antibodies
Shipping Temperature	Blue Ice
Storage Conditions	Store at -20˚ C. Avoid freeze / thaw cycles.
Molecular Weight	Observed: 12kDa
Manufacturer - Research Area	Neuroscience
Background	Cytochrome c oxidase (COX), the terminal enzyme of the mitochondrial respiratory chain, catalyzes the electron transfer from reduced cytochrome c to oxygen. It is a heteromeric complex consisting of 3 catalytic subunits encoded by mitochondrial genes and multiple structural subunits encoded by nuclear genes. The mitochondrially-encoded subunits function in the electron transfer and the nuclear-encoded subunits may function in the regulation and assembly of the complex. This nuclear gene encodes polypeptide 1 (liver isoform) of subunit VIa, and polypeptide 1 is found in all non-muscle tissues. Polypeptide 2 (heart/muscle isoform) of subunit VIa is encoded by a different gene, and is present only in striated muscles. These two polypeptides share 66% amino acid sequence identity. It has been reported that there may be several pseudogenes on chromosomes 1, 6, 7q21, 7q31-32 and 12. However, only one pseudogene (COX6A1P) on chromosome 1p31.1 has been documented.
By Type	Neuroscience
Modifications	None
Purification	Affinity purification
Positive Control 1	A-549
Positive Control 2	MCF7
Positive Control 3	Mouse kidney
Positive Control 4	Mouse heart
Positive Control 5	Mouse liver
Positive Control 6	Rat liver
Concentration	batch dependent
Buffer	PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Application Note	WB: 1:200 - 1:2000 IHC: 1:20 - 1:200 IF: 1:50 - 1:200
Immunogen	Recombinant fusion protein containing a sequence corresponding to amino acids 25-109 of human COX6A1 (NP_004364.2).
Clonality	Polyclonal
NCBI Official Name	Cytochrome c oxidase subunit 6A1, mitochondrial
NCBI Organism	Homo sapiens
User Note	Optimal dilutions for each application to be determined by the researcher.

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Menge: 100 uL

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