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GLUL Antibody, KO Validated

ArtNr PRS-19-660-100uL
Hersteller ProSci
Menge 100 uL
Quantity options 100 uL
Kategorie
Typ Antibody Primary
Format Liquid
Applikationen WB, IF, IHC
Specific against Human (Homo sapiens), Mouse (Murine, Mus musculus)
Host Rabbit
Isotype IgG
Konjugat/Tag Unconjugated
NCBI GLUL
ECLASS 10.1 32160702
ECLASS 11.0 32160702
UNSPSC 12352203
Alias GS,GLNS,PIG43,PIG59,GS
Versandbedingung Gekühlt
Lieferbar
Specificity Human,Mouse
Manufacturer - Type
Primary Antibodies
Shipping Temperature
Blue Ice
Storage Conditions
Store at -20˚ C. Avoid freeze / thaw cycles.
Molecular Weight
Observed: 40kDa
Manufacturer - Research Area
Neuroscience
Background
The protein encoded by this gene belongs to the glutamine synthetase family. It catalyzes the synthesis of glutamine from glutamate and ammonia in an ATP-dependent reaction. This protein plays a role in ammonia and glutamate detoxification, acid-base homeostasis, cell signaling, and cell proliferation. Glutamine is an abundant amino acid, and is important to the biosynthesis of several amino acids, pyrimidines, and purines. Mutations in this gene are associated with congenital glutamine deficiency, and overexpression of this gene was observed in some primary liver cancer samples. There are six pseudogenes of this gene found on chromosomes 2, 5, 9, 11, and 12. Alternative splicing results in multiple transcript variants.
By Type
Neuroscience
Badges
KO
Modifications
None
Purification
Affinity purification
Validation
Antibody is Knockout validated.
Positive Control 1
K-562
Positive Control 2
U-87MG
Positive Control 3
Mouse intestine
Positive Control 4
Mouse kidney
Concentration
batch dependent
Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Application Note
WB: 1:500 - 1:2000
IHC: 1:50 - 1:200
IF: 1:50 - 1:200
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 1-373 of human GLUL (NP_001028228.1).
Clonality
Polyclonal
NCBI Official Name
glutamate-ammonia ligase
NCBI Organism
Homo sapiens
User Note
Optimal dilutions for each application to be determined by the researcher.
Validation
Antibody is Knockout validated.

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

Menge: 100 uL
Lieferbar: In stock
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