XRCC5 Antibody

ArtNr	PRS-19-904-100uL
Hersteller	ProSci
Menge	100 uL
Quantity options	100 uL
Kategorie	Oncology Antibodies By Cell Type Carcinoma Cell Biology Cytoskeleton Immunohistochemistry Immunoprecipitation Western Blot Immunofluorescence Primary Antibodies small GTPases Arf Subfamily
Typ	Antibody Primary
Format	Liquid
Applikationen	WB, IF, IP, IHC
Specific against	Human (Homo sapiens), Mouse (Murine, Mus musculus), Rat (Rattus norvegicus)
Host	Rabbit
Isotype	IgG
Konjugat/Tag	Unconjugated
NCBI	XRCC5
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Alias	XRCC5,KU80,KUB2,Ku86,NFIV,KARP1,KARP-1
Versandbedingung	Gekühlt
Lieferbar
Specificity	Human,Mouse,Rat
Manufacturer - Type	Primary Antibodies
Shipping Temperature	Blue Ice
Storage Conditions	Store at -20˚ C. Avoid freeze / thaw cycles.
Molecular Weight	Observed: 86kDa
Manufacturer - Research Area	Other
Background	The protein encoded by this gene is the 80-kilodalton subunit of the Ku heterodimer protein which is also known as ATP-dependant DNA helicase II or DNA repair protein XRCC5. Ku is the DNA-binding component of the DNA-dependent protein kinase, and it functions together with the DNA ligase IV-XRCC4 complex in the repair of DNA double-strand break by non-homologous end joining and the completion of V(D)J recombination events. This gene functionally complements Chinese hamster xrs-6, a mutant defective in DNA double-strand break repair and in ability to undergo V(D)J recombination. A rare microsatellite polymorphism in this gene is associated with cancer in patients of varying radiosensitivity.
By Type	Other
Modifications	None
Purification	Affinity purification
Positive Control 1	SW620
Positive Control 2	293T
Positive Control 3	HeLa
Positive Control 4	HepG2
Concentration	batch dependent
Buffer	PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Application Note	WB: 1:500 - 1:2000 IHC: 1:100 - 1:200 IF: 1:20 - 1:100 IP: 1:50 - 1:200
Immunogen	Recombinant fusion protein containing a sequence corresponding to amino acids 543-732 of human XRCC5 (NP_066964.1).
Clonality	Polyclonal
NCBI Official Name	X-ray repair complementing defective repair in Chinese hamster cells 5 (double-strand-break rejoining)
NCBI Organism	Homo sapiens
User Note	Optimal dilutions for each application to be determined by the researcher.

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Menge: 100 uL

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Lieferung vsl. bis 04.12.2025

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