XRCC5 Antibody

Blue Ice

Observed: 86kDa

The protein encoded by this gene is the 80-kilodalton subunit of the Ku heterodimer protein which is also known as ATP-dependant DNA helicase II or DNA repair protein XRCC5. Ku is the DNA-binding component of the DNA-dependent protein kinase, and it functions together with the DNA ligase IV-XRCC4 complex in the repair of DNA double-strand break by non-homologous end joining and the completion of V(D)J recombination events. This gene functionally complements Chinese hamster xrs-6, a mutant defective in DNA double-strand break repair and in ability to undergo V(D)J recombination. A rare microsatellite polymorphism in this gene is associated with cancer in patients of varying radiosensitivity.

None

SW620

HeLa

batch dependent

WB: 1:500 - 1:2000
IHC: 1:100 - 1:200
IF: 1:20 - 1:100
IP: 1:50 - 1:200

Polyclonal

Homo sapiens