CAST Antibody, KO Validated

Blue Ice

Observed: 130kDa

The protein encoded by this gene is an endogenous calpain (calcium-dependent cysteine protease) inhibitor. It consists of an N-terminal domain L and four repetitive calpain-inhibition domains (domains 1-4), and it is involved in the proteolysis of amyloid precursor protein. The calpain/calpastatin system is involved in numerous membrane fusion events, such as neural vesicle exocytosis and platelet and red-cell aggregation. The encoded protein is also thought to affect the expression levels of genes encoding structural or regulatory proteins. Alternatively spliced transcript variants encoding different isoforms have been described.

KO

Affinity purification

A-549

MCF-7

Mouse lung

batch dependent

WB: 1:500 - 1:2000

Polyclonal

Homo sapiens

Antibody is Knockout validated.