Vergleich

Anti-Citrate Synthase Mouse mAb

ArtNr PTM-6774
Hersteller PTM Biolabs
Menge 100 ul
Kategorie
Typ Antibody Monoclonal
Format Lyophilized powder
Applikationen WB, ICC, IHC-P
Clon JMMR-3604
Specific against Human (Homo sapiens), Mouse (Murine, Mus musculus), Rat (Rattus norvegicus)
Host Mouse
Isotype IgG1
Konjugat/Tag Unconjugated
Citations Meng Wang, et al. Astragaloside IV protects renal tubular epithelial cells against oxidative stress-induced injury by upregulating CPT1A-mediated HSD17B10 lysine succinylation in diabetic kidney disease. PHYTOTHERAPY RESEARCH, 2024. https://onlinelibrary.wiley.com/doi/abs/10.1002/ptr.8298.
ECLASS 10.1 42030590
ECLASS 11.0 42030590
UNSPSC 12352203
Alias CS
Versandbedingung Raumtemperatur
Lieferbar
Manufacturer - Type
Primary Antibodies
Manufacturer - Applications
WB, IHC-P, ICC/IF
Manufacturer - Category
Uncategorized
Manufacturer - Targets
Citrate Synthase
Shipping Temperature
Ambient temperature
Storage Conditions
Store at -20°C. Avoid freeze/thaw cycles.
Stability
Stable for 12 months from date of receipt/reconstitution.
Manufacturer - Research Area
Signal Transduction, Metabolism
Product description
Citrate synthase (CS) is a mitochondrial enzyme that catalyzes the first and rate-limiting reaction of the citric acid cycle. The enzyme is responsible for the conversion of oxaloacetate and acetyl-CoA to citrate and CoA. Research studies show that CS knockdown HeLa cells are more malignant than vector-transfected cells from an in vivo xenograft model, which suggests a direct link between the Warburg Effect and tumor growth. Intervertebral disc degeneration, a growing health problem, has been linked to changes in citrate synthase activity.
Purification Method
Protein A purified
Formula
PBS, Glycerol, BSA
PTM
Unmodified
Clonality
Recombinant Monoclonal
Background
Citrate synthase (CS) is a mitochondrial enzyme that catalyzes the first and rate-limiting reaction of the citric acid cycle. The enzyme is responsible for the conversion of oxaloacetate and acetyl-CoA to citrate and CoA. Research studies show that CS knockdown HeLa cells are more malignant than vector-transfected cells from an in vivo xenograft model, which suggests a direct link between the Warburg Effect and tumor growth. Intervertebral disc degeneration, a growing health problem, has been linked to changes in citrate synthase activity.
Cellular Localization
Mitochondrion matrix

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

Menge: 100 ul
Lieferbar: In stock
lieferbar

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