CP-1(R) High Grade (KYO-27206) bei Hölzel-Diagnostika

Kategorie

Specific against

other

ArtNr

KYO-27206

eClass 9.0

42051003

Product Description

For cryopreservation of hematopoieticstem cells, dimethyl sulfoxide (DMSO) has generally been used as a cryoprotectant.

In the case ofcryopreservation with DMSO alone, it was common to be stored in liquid nitrogen (-196° C) after frozen by the stepwisefreezing method with a program freezer. However, from the early 1980' s, simple cell freezing methods that do not use a program freezer have been studiedusing DMSO and hydroxyethyl starch (HES) for hematopoietic stem cells in bone marrow.

In Japan, studies on application of simple cell freezing method using DMSO and HES toperipheral blood stem cells have beenadvanced, and the optimum concentrations of HES and DMSO in the simple cell freezing method were decided 6% HES, 5% DMSO. This simple cell freezing method enabled stable cryopreservation for a short period of time (6 months to 1 year and a half) using a -80° C freezer without stepwise freezing method.

Features

Confirmed eligibility for product materials such as regenerative medicine ^{* 1}
Registered drug substance, etc. Registered (MF)
Manufactured at our GMP-compatible facility in Japan
Non-clinical safety test completed
Uses USP grade DMSO
Free of animal-derived ingredients
Disclosure of composition
Perform sterility test, endotoxin, mycoplasma denial test
Final DMSO concentration is 5%

Composition information

Hydroxyethyl starch
Dimethyl sulfoxide
Saline

Examples of cells that can be frozen with CP-1 ^® High Grade

Adhesive cells
Human iPS cells
Floating cells	Mouse hybridoma

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