« Zurück
Home /
Recombinant Human LILRA4/ILT-7/CD85g Protein

Recombinant Human LILRA4/ILT-7/CD85g Protein

ArtNr	RP02708-500ug
Hersteller	Abclonal
Menge	500 ug
Quantity options	100 ug 500 ug
Specific against	Human (Homo sapiens)
Purity	> 95% as determined by Tris-Bis PAGE;> 95% as determined by HPLC
NCBI	LILRA4/CD85g
Alias	CD85g,ILT7,ILT-7,ILT7MGC129598,LILRA4,MGC129597
Versandbedingung	Gekühlt
Lieferbar
Manufacturer - Applications	Less than 1EU per μg by the LAL method.
Manufacturer - Category	Proteins
Shipping Temperature	ice pack
Storage Conditions	Store at -20°C.Store the lyophilized protein at -20°C to -80°C up to 1 year from the date of receipt. \|After reconstitution, the protein solution is stable at -20°C for 3 months, at 2-8°C for up to 1 week.
Protein Weight	49.5 kDa
Description	Recombinant Human LILRA4/ILT-7/CD85g Protein is produced by HEK293 cells expression system. The target protein is expressed with sequence (Glu24-Asn446) of Human LILRA4/ILT-7/CD85g (Accession #) fused with His tag and Avi tag at the C-terminal.
Background	LILRA4, also known as ILT7 and CD85g, is an approximately 60-70 kDa variably glycosylated transmembrane protein that regulates immune cell activation. Mature human LILRA4 consists of a 423 amino acid (aa) extracellular domain (ECD) with four immunoglobulin-like domains, a 21 aa transmembrane segment, and a 32 aa cytoplasmic domain.LILRA4 function coreceptor to limit the innate immune responses to viral infections; signaling occurs via FCER1G (PubMed:16735691, PubMed:19564354). Down-regulates the production of IFNA1, IFNA2, IFNA4, IFNB1 and TNF by plasmacytoid dendritic cells that have been exposed to influenza virus or cytidine-phosphate-guanosine (CpG) dinucleotides, indicating it functions as negative regulator of TLR7 and TLR9 signaling cascades.
Manufacturer - Cross Reactivity	Centrifuge the tube before opening. Reconstitute to a concentration of 0.1-0.5 mg/mL in sterile distilled water. Avoid vortex or vigorously pipetting the protein. For long term storage, it is recommended to add a carrier protein or stablizer (e.g. 0.1% BSA, 5% HSA, 10% FBS or 5% Trehalose), and aliquot the reconstituted protein solution to minimize free-thaw cycles.
Immunogen	Glu24-Asn446
Route	C-His&Avi
Manufacturer - Research Area	Other Recombinant Protein
Expected Protein Size	49.5 kDa
Gene Symbol	LILRA4/CD85g

Hinweis: Die dargestellten Informationen und Dokumente (Bedienungsanleitung, Produktdatenblatt, Sicherheitsdatenblatt und Analysezertifikat) entsprechen unserem letzten Update und sollten lediglich der Orientierung dienen. Wir übernehmen keine Garantie für die Aktualität. Für spezifische Anforderungen bitten wir Sie, uns eine Anfrage zu stellen.

Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

Arbeitsanleitung (Data Sheet) anfordern

Produkdatenblatt anfordern

Sicherheitsdatenblatt anfordern

Einfache Bestellung Periodische Bestellung

Menge: 500 ug

lieferbar

Lieferung vsl. bis 03.07.2025

Express-Lieferung: 6 Tage sparen

Vergleichen

Auf den Wunschzettel

Weiterempfehlen per Mail