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Recombinant Human PD-L1/B7-H1 Protein (ECD, hFc Tag), HPLC-verified

Recombinant Human PD-L1/B7-H1 Protein (ECD, hFc Tag), HPLC-verified

ArtNr	10084-H02H-4
Hersteller	Sino Biological
Menge	4 mg
Quantity options	1 mg 100 ug 2 mg 4 mg
Kategorie	Oncology By Cell Type Blastoma Carcinoma Glioma Hematology Lymphoma Melanoma Sarcoma Peptides & Proteins Recombinant Proteins Myelofibrosis Mesothelioma
Typ	Proteins
Specific against	Human (Homo sapiens)
Host	Human
ECLASS 10.1	32160409
ECLASS 11.0	32160409
UNSPSC	12352202
Alias	B7-H, B7-H1, B7H1, PD-L1, PDCD1L1, PDCD1LG1, PDL1
Similar products	CD274
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Manufacturer - Category	Protein
Molecule	CD274
Synonym	B7-H, B7-H1, B7H1, PD-L1, PDCD1L1, PDCD1LG1, PDL1
Storage	Store it under sterile conditions at -20C to -80C. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
Shipping	In general, recombinant proteins are provided as lyophilized powder which are shipped at ambient temperature. Bulk packages of recombinant proteins are provided as frozen liquid. They are shipped out with blue ice unless customers require otherwise.
Protein Construction	A DNA sequence encoding the N-terminal segment (Met 1-Thr 239) of the extracellular domain of human B7-H1 (NP_054862.1) was expressed with C-terminal fused Fc region of human IgG1.
Expressed Host	Human Cells
Purity	> 95 % as determined by SDS-PAGE
Bio-Activity	Measured by its binding ability in a functional ELISA . Immobilized human PD-1 at 10 ug/ml (100 ul/well) can bind recombinant human B7-H1 / PD-L1 / Fc chimera with a linear range of 0.02-0.4 ug/ml .
Endotoxin	< 1.0 EU per ug of the protein as determined by the LAL method
Predicted N Terminal	Phe 19
Molecule Mass	The recombinant mature human B7-H1/Fc is a disulfide-linked homodimeric protein. The reduced monomer consists of 459 amino acids and predicts a molecular mass of 52 kDa. As a result of glycosylation, the rh B7-H1/Fc monomer migrates as an approximately 65-70 kDa protein in SDS-PAGE under reducing conditions.
Formulation	Lyophilized from sterile PBS, pH 7.4
Accession	NP_054862.1
Amino acid sequence	Met1-Thr239
TAG	C-human IgG1-Fc

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

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10084-H02H-4-datasheet.pdf

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Menge: 4 mg

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