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Recombinant Human Fas/CD95/TNFRSF6 Protein (hFc Tag)

Recombinant Human Fas/CD95/TNFRSF6 Protein (hFc Tag)

ArtNr	10217-H02H-4
Hersteller	Sino Biological
Menge	4 mg
Quantity options	1 mg 100 ug 2 mg 4 mg
Kategorie	Oncology Metabolism Diabetes Cholesterol & Lipid Metabolism By Cell Type Carcinoma Peptides & Proteins Recombinant Proteins Cell Biology Cell Status Apoptosis Enzymes Fatty Acid Synthesis
Typ	Proteins
Specific against	Human (Homo sapiens)
Host	Human
ECLASS 10.1	32160409
ECLASS 11.0	32160409
UNSPSC	12352202
Alias	ALPS1A, APO-1, APT1, CD95, FAS1, FASTM, TNFRSF6
Similar products	FAS
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Manufacturer - Category	Protein
Molecule	FAS
Synonym	ALPS1A, APO-1, APT1, CD95, FAS1, FASTM, TNFRSF6
Storage	Store it under sterile conditions at -20C to -80C. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
Shipping	In general, recombinant proteins are provided as lyophilized powder which are shipped at ambient temperature. Bulk packages of recombinant proteins are provided as frozen liquid. They are shipped out with blue ice unless customers require otherwise.
Protein Construction	A DNA sequence encoding the extracellular domain (Met 1-Glu 173) of human Fas antigen (NP_000034.1) was fused with the Fc region of human IgG1 at the C-terminus.
Expressed Host	Human Cells
Purity	(75.9+20.9) % as determined by SDS-PAGE
Bio-Activity	Measured by its ability to inhibit Fas Ligand induced apoptosis of Jurkat human acute T cell leukemia cells. The ED50 for this effect is typically 0.02-0.1 ug/mL in the presence of 20 ng/mL recombinant human Fas ligand.
Endotoxin	< 1.0 EU per ug of the protein as determined by the LAL method
Predicted N Terminal	Gln 26
Molecule Mass	The recombinant human Fas/Fc chimera is a disulfide-linked homodimeric protein generated after removal of the signal peptide. The reduced monomer consists of 386 amino acids and has a predicted molecular mass of 43.4 kDa. In SDS-PAGE under reducing conditions, the monomer migrates as an approximately 55-60 kDa protein due to glycosylation.
Formulation	Lyophilized from sterile PBS, pH 7.4
Accession	NP_000034.1
Amino acid sequence	Met1-Glu173
TAG	C-human IgG1-Fc

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

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10217-H02H-4-datasheet.pdf

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Menge: 4 mg

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