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Human TGFBR2 Protein (His & Fc Tag)

Human TGFBR2 Protein (His & Fc Tag)

ArtNr	10358-H03H-20
Hersteller	Sino Biological
Menge	20 ug
Quantity options	1 mg 2 mg 20 ug 4 mg 50 ug
Kategorie	Oncology Neuroscience Neuroinflammation By Cell Type Carcinoma Glioma Peptides & Proteins Recombinant Proteins Cell Biology Cell Culture Cytokines Mesothelioma By Organ Colorectal Cancer
Typ	Proteins
Specific against	Human (Homo sapiens)
Host	Human
Konjugat/Tag	HIS, Fc
Purity	> 97 % as determined by SDS-PAGE
Sequence	Met1-Asp159
ECLASS 10.1	32160409
ECLASS 11.0	32160409
UNSPSC	12352202
Alias	AAT3,FAA3,LDS1B,LDS2,LDS2B,MFS2,RIIC,TAAD2,TGFbeta-RII,TGFR-2
Similar products	TGFBR2
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Manufacturer - Conjugate / Tag	C-human IgG1-Fc & His
Shipping Temperature	In general, recombinant proteins are provided as lyophilized powder which are shipped at ambient temperature. Bulk packages of recombinant proteins are provided as frozen liquid. They are shipped out with blue ice unless customers require otherwise.
Storage Conditions	Store it under sterile conditions at -20C to -80C. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
Antigen molecule name	TGFBR2
Protein Construction	A DNA sequence encoding the extracellular domain (Met 1-Asp 159) of human TGFbeta receptor 2 (NP_003233.4) was expressed with the fused C-terminal His-tagged Fc region of human IgG1 at the C-terminus.
Expressed Host	Human Cells
Bio-Activity	Measured by its ability to inhibit TGF-beta1 activity on Mv-1-lu mink lung epithelial cells. The ED50 for this effect is typically 0.2-3.0 ug/ml in the presence of 1 ng/mL of recombinant human TGF-beta1.
Endotoxin	< 1.0 EU per ug of the protein as determined by the LAL method
Predicted N Terminal	Ile 24
Molecule Mass	The recombinant human TGFbeta R2/Fc is a disulfide-linked homodimeric protein after removal of the signal peptide. The monomer consists of 383 amino acids and predicts a molecular mass of 43.4 kDa. By SDS-PAGE under reducing conditions, the apparent molecular mass of this monomer is approximately 60-65 kDa due to the glycosylation.
Formulation	Lyophilized from sterile 100mM Glycine, 10mM NaCl, 50mM Tris, pH 7.5

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

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Menge: 20 ug

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