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Recombinant Human VE-Cadherin Protein (His & hFc Tag)

Recombinant Human VE-Cadherin Protein (His & hFc Tag)

ArtNr	10433-H03H-100
Hersteller	Sino Biological
Menge	100 ug
Quantity options	1 mg 100 ug 2 mg 4 mg
Kategorie	Oncology Neuroscience Neural Adhesion Molecules By Cell Type Carcinoma Peptides & Proteins Recombinant Proteins By Organ Bladder Cancer
Typ	Proteins
Specific against	Human (Homo sapiens)
ECLASS 10.1	32160409
ECLASS 11.0	32160409
UNSPSC	12352202
Alias	7B4, CD144
Similar products	CDH5
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Manufacturer - Category	Protein
Molecule	CDH5
Synonym	7B4, CD144
Storage	Store it under sterile conditions at -20C to -80C. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
Shipping	In general, recombinant proteins are provided as lyophilized powder which are shipped at ambient temperature. Bulk packages of recombinant proteins are provided as frozen liquid. They are shipped out with blue ice unless customers require otherwise.
Protein Construction	A DNA sequence encoding the extracellular domain of human CDH5 (NP_001786.2) (Met 1-Gln 593) was fused with the C-terminal polyhistidine-tagged Fc region of human IgG1 at the C-terminus.
Expressed Host	Human Cells
Purity	> 85 % as determined by SDS-PAGE
Bio-Activity	Measured by the ability of the immobilized protein to support the adhesion of MCF-7 human breast adenocarcinoma cells. When 5 x 10E4 cells/well are added to Recombinant Human Cadherin-5 coated plates (0.8 ug/mL with 100 uL/well), approximately >50% will adhere after 1 hour at 37C.
Endotoxin	< 1.0 EU per ug of the protein as determined by the LAL method
Predicted N Terminal	Ala 26
Molecule Mass	The recombinant human CDH5/Fc is a disulfide-linked homodimeric protein. The reduced monomer consists of 815 amino acids after removal of the signal peptide and has a predicted molecular mass of 92 kDa. In SDS-PAGE under reducing conditions, the apparent molecular mass of rh CDH5/Fc monomer is approximately 120 kDa due to glycosylation.
Formulation	Lyophilized from sterile PBS, pH 7.4
Accession	NP_001786.2
Amino acid sequence	Met1-Gln593
TAG	C-human IgG1-Fc & His

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

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10433-H03H-100-datasheet.pdf

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