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Recombinant Human TGF-beta RI Protein (His & hFc Tag)

Recombinant Human TGF-beta RI Protein (His & hFc Tag)

ArtNr	10459-H03H-10
Hersteller	Sino Biological
Menge	10 ug
Quantity options	1 mg 10 ug 100 ug 2 mg 20 ug 4 mg
Kategorie	Oncology Neuroscience Neuroinflammation Molecular Targets for Neuroscience By Cell Type Carcinoma Glioma Hematology Lymphoma Melanoma Sarcoma Peptides & Proteins Recombinant Proteins Cell Biology Cell Culture Cytokines Mesothelioma By Organ Colorectal Cancer
Typ	Proteins
Specific against	Human (Homo sapiens)
Host	Human
Konjugat/Tag	HIS, Fc
Purity	> 85 % as determined by SDS-PAGE
Sequence	Met1-Glu125
ECLASS 10.1	32160409
ECLASS 11.0	32160409
UNSPSC	12352202
Alias	AAT5,ACVRLK4,ALK-5,ALK5,ESS1,LDS1,LDS1A,LDS2A,MSSE,SKR4,tbetaR-I,TGFR-1
Similar products	TGFBR1
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Manufacturer - Conjugate / Tag	C-human IgG1-Fc & His
Shipping Temperature	In general, recombinant proteins are provided as lyophilized powder which are shipped at ambient temperature. Bulk packages of recombinant proteins are provided as frozen liquid. They are shipped out with blue ice unless customers require otherwise.
Storage Conditions	Store it under sterile conditions at -20C to -80C. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
Antigen molecule name	TGFBR1
Protein Construction	A DNA sequence encoding the human TGFBR1 (NP_004603.1) extracellular domain (Met 1-Glu 125) was fused with the C-terminal polyhistidine-tagged Fc region of human IgG1 at the C-terminus.
Expressed Host	Human Cells
Bio-Activity	1. Measured by its binding ability in a functional ELISA. Immobilized mouse CD105 at 10 ug/ml (100 ul/well) can bind human TGFRB1 with a linear ranger of 6.4-800 ng/ml. 2. Measured by its ability to bind human CD105 in a functional ELISA.
Endotoxin	< 1.0 EU per ug of the protein as determined by the LAL method
Predicted N Terminal	Ala 25
Molecule Mass	The recombinant human TGFBR1/Fc is a disulfide-linked homodimer. The reduced monomer consists of 349 amino acids and has a predicted molecular mass of 38.8 kDa. As a result of glycosylation, the apparent molecular mass of rh TGFBR1/Fc monomer is approximately 45-50 kDa in SDS-PAGE under reducing conditions, with ca.10% free Fc fragments.
Formulation	Lyophilized from sterile PBS, pH 7.4

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

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10459-H03H-10-datasheet.pdf

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Menge: 10 ug

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