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Recombinant Human TrkA Protein (His & hFc Tag), HPLC-verified Europäischer Partner

ArtNr 11073-H03H-4
Hersteller Sino Biological
Menge 4 mg
Quantity options 1 mg 100 ug 2 mg 4 mg
Kategorie
Typ Proteins
Specific against Human (Homo sapiens)
Host Human
ECLASS 10.1 32160409
ECLASS 11.0 32160409
UNSPSC 12352202
Alias MTC, p140-TrkA, TRK, Trk-A, TRK1, TRKA
Similar products NTRK1
Lieferbar
Manufacturer - Category
Protein
Molecule
NTRK1
Synonym
MTC, p140-TrkA, TRK, Trk-A, TRK1, TRKA
Storage
Store it under sterile conditions at -20C to -80C. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
Shipping
In general, recombinant proteins are provided as lyophilized powder which are shipped at ambient temperature.
Bulk packages of recombinant proteins are provided as frozen liquid. They are shipped out with blue ice unless customers require otherwise.
Protein Construction
A DNA sequence encoding the human NTRK1 (NP_002520.2) extracellular domain (Met 1-Pro 382) was fused with the C-terminal polyhistidine-tagged Fc region of human IgG1 at the C-terminus.
Expressed Host
Human Cells
Purity
> 98 % as determined by SDS-PAGE
Bio-Activity
Measured by its ability to inhibit NGF-induced proliferation of TF-1 human erythroleukemic cells. The ED50 for this effect is typically 0.04-0.15 ug/ml in the presence of 10 ng/ml of recombinant human NGF.
Endotoxin
< 1.0 EU per ug of the protein as determined by the LAL method
Predicted N Terminal
Ala 33
Molecule Mass
The recombinant human NTRK1/Fc is a disulfide-linked homodimer. The reduced monomer consists of 598 amino acids and has a predicted molecular mass of 66 kDa. In SDS-PAGE under reducing conditions, the apparent molecular mass of rh NTRK1/Fc monomer is approximately 85-95 kDa due to glycosylation.
Formulation
Lyophilized from sterile PBS, pH 7.4
Accession
NP_002520.2
Amino acid sequence
Met1-Pro382
TAG
C-human IgG1-Fc & His

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

Menge: 4 mg
Lieferbar: In stock
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