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Recombinant Human Insulin Receptor Protein (ECD, long isoform, His Tag), HPLC-verified

Recombinant Human Insulin Receptor Protein (ECD, long isoform, His Tag), HPLC-verified

ArtNr	11081-H08H-100
Hersteller	Sino Biological
Menge	100 ug
Quantity options	1 mg 100 ug 2 mg 4 mg
Kategorie	Oncology Metabolism Diabetes Glucose Homeostasis Cholesterol & Lipid Metabolism Regulation of Appetite By Cell Type Blastoma Carcinoma Peptides & Proteins Recombinant Proteins Endocrine Regulation of Lipid Metabolism
Typ	Proteins
Format	Human Cell
Specific against	Human (Homo sapiens)
Host	Human
ECLASS 10.1	32160409
ECLASS 11.0	32160409
UNSPSC	12352202
Alias	CD220, HHF5, Insulin Receptor
Similar products	INSR
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Manufacturer - Category	Protein
Molecule	INSR
Synonym	CD220, HHF5, Insulin Receptor
Storage	Store it under sterile conditions at -20C to -80C. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
Shipping	In general, recombinant proteins are provided as lyophilized powder which are shipped at ambient temperature. Bulk packages of recombinant proteins are provided as frozen liquid. They are shipped out with blue ice unless customers require otherwise.
Protein Construction	A DNA sequence encoding the human INSR isoform long (NP_000199.2) extracellular domain (Met 1-Lys 956) was expressed, fused with a polyhistidine tag at the C-terminus.
Expressed Host	Human Cells
Purity	> 95 % as determined by SDS-PAGE
Bio-Activity	Measured by its binding ability in a functional ELISA . When 1 ug/ml of biotinylated human insulin is immobilized onto a streptavidin coated plate, it can bind human INSR (isoform long) with a linear range of 0.625-10 ug/ml .
Endotoxin	< 1.0 EU per ug of the protein as determined by the LAL method
Predicted N Terminal	His 28 & Ser 763
Molecule Mass	The secreted recombinant human INSR isoform long consists of 940 amino acids and has a predicted molecular mass of 107 (83+24) kDa. As a result of glycosylation, the apparent molecular mass of rhINSR is approximately 125-135 kDa & 40-45 kDa, corresponding to the alpha subunit and the ECD of beta subunit respectively in SDS-PAGE under reducing conditions.
Formulation	Lyophilized from sterile PBS, pH 7.4
Accession	NP_000199.2
Amino acid sequence	Met1-Lys956
TAG	C-His

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

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11081-H08H-100-datasheet.pdf

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Menge: 100 ug

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