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Recombinant Human RANKL/TNFSF11 Protein (mFc Tag)

Recombinant Human RANKL/TNFSF11 Protein (mFc Tag)

ArtNr	11682-H04H-2
Hersteller	Sino Biological
Menge	2 mg
Quantity options	1 mg 100 ug 2 mg 20 ug 4 mg 5 ug
Kategorie	Oncology Peptides & Proteins Recombinant Proteins Cell Biology Cell Culture Cytokines By Organ Lymphatic System Cancer
Typ	Proteins
Specific against	Human (Homo sapiens)
Host	Human
Konjugat/Tag	Fc
Purity	> 90 % as determined by SDS-PAGE
Sequence	Gly63-Asp244
ECLASS 10.1	32160409
ECLASS 11.0	32160409
UNSPSC	12352202
Alias	CD254,hRANKL2,ODF,OPGL,OPTB2,RANKL,sOdf,TRANCE
Similar products	TNFSF11
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Manufacturer - Type	Protein
Manufacturer - Conjugate / Tag	N-mouse IgG1-Fc
Shipping Temperature	In general, recombinant proteins are provided as lyophilized powder which are shipped at ambient temperature. Bulk packages of recombinant proteins are provided as frozen liquid. They are shipped out with blue ice unless customers require otherwise.
Storage Conditions	Store it under sterile conditions at -20C to -80C. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
Antigen molecule name	TNFSF11
Protein Construction	A DNA sequence encoding the human TNFSF11 (AAC51762.1) (Gly63-Asp244) was expressed with the Fc region of mouse IgG1 at the N-terminus.
Expressed Host	Human Cells
Bio-Activity	1. Immobilized mouse mFc-TNFSF11 at 10 ug/ml (100 ul/well) can bind biotinylated human TNFRSF11B-His (Cat:10271-H08H), The EC50 of biotinylated human TNFRSF11B-His (Cat:10271-H08H) is 6.0-14.1 ng/ml. 2. The bioactivity of hRANKL was determined by measuring the ability of hRANKL to induce TRAP activity in Raw 264.7 cells. The ED50 for this effect is typically 15-45 ng/mL.
Endotoxin	< 1.0 EU per ug of the protein as determined by the LAL method
Predicted N Terminal	Asp
Molecule Mass	The recombinant human TNFSF11/mFc comprises 418 amino acids and has a predicted molecular mass of 47.1 kDa. The apparent molecular mass of the monomer is approximately 48-56 kDa in SDS-PAGE under reducing conditions due to glycosylation.
Formulation	Lyophilized from sterile PBS, pH 7.4.

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

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11682-H04H-2-datasheet.pdf

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Menge: 2 mg

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