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Recombinant Human, Cynomolgus TWEAK/TNFSF12 Protein (mFc Tag) Europäischer Partner

ArtNr 90094-C04H-50
Hersteller Sino Biological
Menge 50 ug
Quantity options 1 mg 2 mg 20 ug 4 mg 5 ug 50 ug 500 ug
Kategorie
Typ Proteins
Specific against Monkey (Cynomolgus, Simian)
Host Human
Konjugat/Tag Fc
Purity (72.2+25.9) % as determined by SDS-PAGE
Sequence Ser94-His249
ECLASS 10.1 32160409
ECLASS 11.0 32160409
UNSPSC 12352202
Alias 90094-C04H
Similar products TNFSF12
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Manufacturer - Type
Protein
Manufacturer - Conjugate / Tag
N-mouse IgG1-Fc
Shipping Temperature
In general, recombinant proteins are provided as lyophilized powder which are shipped at ambient temperature.
Bulk packages of recombinant proteins are provided as frozen liquid. They are shipped out with blue ice unless customers require otherwise.
Storage Conditions
Store it under sterile conditions at -20C to -80C. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
Antigen molecule name
TNFSF12
Protein Construction
A DNA sequence encoding the cynomolgus TNFSF12 (F7HGN4) (Ser94-His249) was expressed with the Fc region of mouse IgG1 at the N-terminus. Cynomolgus and Human TNFSF12 sequences are identical.
Expressed Host
Human Cells
Bio-Activity
1. Measured in a cell proliferation assay using HUVEC human umbilical vein endothelial cells. The ED50 for this effect is typically 2-8 ng/mL.
2. Immobilized Cynomolgus mFc-TNFSF12 at 10 ug/ml (100 ul/well) can bind human Fc-TNFRSF12A (Cat:10431-H01H), The EC50 of human Fc-TNFRSF12A (Cat:10431-H01H) is 0.07-0.15 ug/ml.
Endotoxin
< 1.0 EU per ug of the protein as determined by the LAL method
Predicted N Terminal
Asp
Molecule Mass
The recombinant cynomolgus TNFSF12 is a disulfide-linked homodimer. The reduced monomer comprises 392 amino acids and has a calculated molecular mass of 43.8 KDa. The apparent molecular mass of it is approximately 34 and 47 KDa respectively in SDS-PAGE.
Formulation
Lyophilized from sterile PBS, pH 7.4

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

Menge: 50 ug
Lieferbar: In stock
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