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Recombinant Mouse Growth Hormone Receptor Protein (His & hFc Tag)

Recombinant Mouse Growth Hormone Receptor Protein (His & hFc Tag)

ArtNr	50043-M03H-2
Hersteller	Sino Biological
Menge	2 mg
Quantity options	1 mg 100 ug 2 mg 4 mg
Kategorie	Oncology Neuroscience Neuroinflammation Metabolism Diabetes Molecular Targets for Neuroscience By Cell Type Peptides & Proteins Recombinant Proteins
Typ	Proteins
Specific against	Mouse (Murine, Mus musculus)
Host	Human
ECLASS 10.1	32160409
ECLASS 11.0	32160409
UNSPSC	12352202
Alias	GHBP, GHR/BP
Similar products	GHR
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Manufacturer - Category	Protein
Molecule	GHR
Synonym	GHBP, GHR/BP
Storage	Store it under sterile conditions at -20C to -80C. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
Shipping	In general, recombinant proteins are provided as lyophilized powder which are shipped at ambient temperature. Bulk packages of recombinant proteins are provided as frozen liquid. They are shipped out with blue ice unless customers require otherwise.
Protein Construction	A DNA sequence encoding the extracellular domain (Met 1-Gln 273) of mouse GHR (NP_034414.2) precursor was fused with the C-terminal polyhistidine-tagged Fc region of human IgG1 at the C-terminus.
Expressed Host	Human Cells
Purity	> 85 % as determined by SDS-PAGE
Bio-Activity	Measured by its ability to inhibit proliferation of INS-1 cells induced by human growth hormone. The ED50 for this effect is 0.5-2 ug/mL in the presence of 50 ng/mL human growth hormone.
Endotoxin	< 1.0 EU per ug of the protein as determined by the LAL method
Predicted N Terminal	Thr 25
Molecule Mass	The recombinant mouse GHR/Fc is a disulfide-linked homodimer after removal of the signal peptide. The reduced monomer consists of 497 amino acids and has a predicted molecular mass of 56.8 kDa. In SDS-PAGE under reducing conditions, the apparent molecular mass of rmGHR/Fc monomer is approximately 70-80 kDa due to glycosylation.
Formulation	Lyophilized from sterile PBS, pH 7.4
Accession	NP_034414.2
Amino acid sequence	Met1-Gln273
TAG	C-human IgG1-Fc & His

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

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50043-M03H-2-datasheet.pdf

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Menge: 2 mg

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