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Recombinant Mouse BMPR1A/ALK-3 Protein (His & hFc Tag) Europäischer Partner

ArtNr 50078-M03H-1
Hersteller Sino Biological
Menge 1 mg
Quantity options 1 mg 100 ug 2 mg 200 ug 4 mg
Kategorie
Typ Proteins
Specific against Mouse (Murine, Mus musculus)
Host Human
Konjugat/Tag HIS, Fc
Purity > 95 % as determined by SDS-PAGE
Sequence Met1-Arg152
ECLASS 10.1 32160409
ECLASS 11.0 32160409
UNSPSC 12352202
Alias 1110037I22Rik,ALK3,AU045487,Bmpr,BMPR-IA
Similar products BMPR1A
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Manufacturer - Type
Protein
Manufacturer - Conjugate / Tag
C-human IgG1-Fc & His
Shipping Temperature
In general, recombinant proteins are provided as lyophilized powder which are shipped at ambient temperature.
Bulk packages of recombinant proteins are provided as frozen liquid. They are shipped out with blue ice unless customers require otherwise.
Storage Conditions
Store it under sterile conditions at -20C to -80C. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
Antigen molecule name
BMPR1A
Protein Construction
A DNA sequence encoding the extracellular domain (Met 1-Arg 152) of mouse ALK3 (NP_033888.2) precursor was fused with the Fc region of human IgG1 at the C-terminus.
Expressed Host
Human Cells
Bio-Activity
Measured by its ability to inhibit BMP4-induced activity in MC3T3-E1 Mouse osteoblastic cells. The ED50 for this effect is typically 0.1-0.3 ug/ml in the presence of 50 ng/mL of recombinant human BMP4.
Endotoxin
< 1.0 EU per ug of the protein as determined by the LAL method
Predicted N Terminal
Gln 24
Molecule Mass
The recombinant mouse ALK3/Fc is a disulfide-linked homodimer after removal of the signal peptide. The reduced monomer consists of 376 amino acids and has a predicted molecular mass of 42 kDa. In SDS-PAGE under reducing conditions, the apparent molecular mass of rm ALK3/Fc monomer is approximately 60 kDa due to glycosylation.
Formulation
Lyophilized from sterile PBS, pH 7.4

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

Menge: 1 mg
Lieferbar: In stock
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