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Recombinant Mouse Endoglin/CD105 Protein (His Tag), HPLC-verified

Recombinant Mouse Endoglin/CD105 Protein (His Tag), HPLC-verified

ArtNr	50407-M08H-100
Hersteller	Sino Biological
Menge	100 ug
Quantity options	1 mg 100 ug 2 mg 4 mg
Kategorie	Oncology Neuroscience Neural Lineage Markers Neuroinflammation Molecular Targets for Neuroscience Neural Development By Cell Type Carcinoma Peptides & Proteins Recombinant Proteins Adhesion Molecule Markers
Typ	Proteins
Format	Human Cell
Specific against	Mouse (Murine, Mus musculus)
Host	Human
ECLASS 10.1	32160409
ECLASS 11.0	32160409
UNSPSC	12352202
Alias	AI528660, AI662476, CD105, Endo, S-endoglin
Similar products	ENG
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Manufacturer - Category	Protein
Molecule	ENG
Synonym	AI528660, AI662476, CD105, Endo, S-endoglin
Storage	Store it under sterile conditions at -20C to -80C. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
Shipping	In general, recombinant proteins are provided as lyophilized powder which are shipped at ambient temperature. Bulk packages of recombinant proteins are provided as frozen liquid. They are shipped out with blue ice unless customers require otherwise.
Protein Construction	A DNA sequence encoding the mouse CD105 (NP_031958.2) extracellular domain (Met 1-Gly 580) was expressed, with a C-terminal polyhistidine tag.
Expressed Host	Human Cells
Purity	> 97 % as determined by SDS-PAGE
Bio-Activity	1. Measured by its ability to bind Human ENG-Fc (Cat:10149-H02H) in functional Elisa. 2. Measured by its ability to latent TGFB1-His (Cat:10804-H08H) in functional Elisa. 3. Measured by its ability to mouse ENG-His (Cat:50407-M08H) in functional Elisa. 4. Measured by its ability to inhibit BMP9-induced alkaline phosphatase production by MC3T3E1 mouse chondrogenic cells. David, L. et al. (2007) Blood 109:1953. The ED50 for this effect is typically 5-15 ng/mL in the presence of 2 ng/mL of recombiant human BMP9.
Endotoxin	< 1.0 EU per ug of the protein as determined by the LAL method
Predicted N Terminal	Arg 27
Molecule Mass	The secreted recombinant mouse CD105 consists of 565 amino acids and has a calculated molecular mass of 61.2 kDa. As a result of glycosylation, the apparent molecular mass of the recombinant protein is approximately 65-70 kDa in SDS-PAGE under reducing conditions.
Formulation	Lyophilized from sterile PBS, pH 7.4
Accession	NP_031958.2
Amino acid sequence	Met1-Gly580
TAG	C-His

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

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50407-M08H-100-datasheet.pdf

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Menge: 100 ug

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