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Recombinant Mouse VEGFR3/FLT4 Protein (hFc Tag)

Recombinant Mouse VEGFR3/FLT4 Protein (hFc Tag)

ArtNr	50584-M02H-4
Hersteller	Sino Biological
Menge	4 mg
Quantity options	1 mg 100 ug 2 mg 4 mg 50 ug
Kategorie	Oncology By Cell Type Blastoma Carcinoma Hematology Lymphoma Myeloma Melanoma Sarcoma Peptides & Proteins Recombinant Proteins Cell Biology Cell Movement Cell Adhesion Cell Culture Cytokines Adenocarcinoma By Organ Bladder Cancer
Typ	Proteins
Specific against	Mouse (Murine, Mus musculus)
Host	Human
Konjugat/Tag	Fc
Purity	> 92 % as determined by SDS-PAGE
Sequence	Met1-Glu775
ECLASS 10.1	32160409
ECLASS 11.0	32160409
UNSPSC	12352202
Alias	AI323512,Chy,Flt-4,VEGFR-3,VEGFR3
Similar products	FLT4
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Manufacturer - Type	Protein
Manufacturer - Conjugate / Tag	C-human IgG1-Fc
Shipping Temperature	In general, recombinant proteins are provided as lyophilized powder which are shipped at ambient temperature. Bulk packages of recombinant proteins are provided as frozen liquid. They are shipped out with blue ice unless customers require otherwise.
Storage Conditions	Store it under sterile conditions at -20C to -80C. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
Antigen molecule name	FLT4
Protein Construction	A DNA sequence encoding the mouse FLT4 (P35917-1) extracellular domain (Met 1-Glu 775) was was fused with the Fc region of human IgG1 at the C-terminus.
Expressed Host	Human Cells
Bio-Activity	1. Measured by its ability to bind human VEGF-D (Cat: 10557-H08H) in functional ELISA. 2. Immobilized human VEGF-C (Cat: 10542-H08H) at 10 ug/mL (100 uL/well) can bind mouse VEGFR3-Fc. The EC50 of mouse VEGFR3-Fc is 0.008 ug/mL. 3. Measured by its ability to bind with mouse FIGF-His (Cat:50157-M08H) in a functional ELISA.
Endotoxin	< 1.0 EU per ug of the protein as determined by the LAL method
Predicted N Terminal	Tyr 25
Molecule Mass	The secreted recombinant mouse FLT4/Fc chimera is a disulfide-linked homodimer. The reduced monomer consists of 992 amino acids and has a predicted molecular mass of 112 kDa. As a result of glycosylation and proteolytic cleavage, rm FLT4/Fc monomer migrates as three bands (150, 85, 65 kDa) corresponding to the full length and the cleaved two polypeptides respectively in SDS-PAGE under reducing conditions.
Formulation	Lyophilized from sterile PBS, pH 7.4

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

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50584-M02H-4-datasheet.pdf

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Menge: 4 mg

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