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Recombinant Rat ALK-1 Protein (His & hFc Tag) Europäischer Partner

ArtNr 10596-R03H-1
Hersteller Sino Biological
Menge 1 mg
Quantity options 1 mg 100 ug 2 mg 200 ug 4 mg
Kategorie
Typ Proteins
Specific against Rat (Rattus norvegicus)
Konjugat/Tag HIS, Fc
Purity > 90 % as determined by SDS-PAGE
Sequence Met1-Ala118
ECLASS 10.1 32160409
ECLASS 11.0 32160409
UNSPSC 12352202
Alias 10596-R03H
Similar products ACVRL1
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Manufacturer - Type
Protein
Manufacturer - Conjugate / Tag
C-human IgG1-Fc & His
Shipping Temperature
In general, recombinant proteins are provided as lyophilized powder which are shipped at ambient temperature.
Bulk packages of recombinant proteins are provided as frozen liquid. They are shipped out with blue ice unless customers require otherwise.
Storage Conditions
Store it under sterile conditions at -20C to -80C. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
Antigen molecule name
ACVRL1
Protein Construction
A synthetic DNA sequence encoding the rat ACVRL1 (NP_071886.1) extracellular domain (Met 1-Ala 118) was fused with the C-terminal polyhistidine-tagged Fc region of human IgG1 at the C-terminus.
Expressed Host
Human Cells
Bio-Activity
Measured by its ability to inhibit BMP9-induced alkaline phosphatase production by MC3T3E1 mouse chondrogenic cells. David, L. et al. (2007) Blood 109:1953.
The ED50 for this effect is typically 40-200 ng/mL in the presence of 2 ng/mL of recombiant human BMP9.
Endotoxin
< 1.0 EU per ug of the protein as determined by the LAL method
Predicted N Terminal
Asp 17
Molecule Mass
The secreted recombinant rat ACVRL1/Fc is a disulfide-linked homodimer after removal of the signal peptide. The reduced monomer comprises 343 amino acids with a predicted molecular mass of 38.7 kDa. As a result of glycosylation, it migrates as an approximately 50-55 kDa band in SDS-PAGE under reducing conditions.
Formulation
Lyophilized from sterile PBS, pH 7.4

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

Menge: 1 mg
Lieferbar: In stock
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