Anti-BACE antibody

Polyclonal

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

P56817

1 mg/ml

23621

Synthesized peptide derived from human BACE around the non-phosphorylation site of S498.

Rabbit polyclonal against BACE

Cell Membrane
Single-Pass Type I Membrane Protein
Golgi Apparatus
Trans-Golgi Network
Endoplasmic Reticulum
Endosome
Cell Surface
Cytoplasmic Vesicle Membrane
Membrane Raft
Lysosome
Late Endosome
Early Endosome
Recycling Endosome
Cell Projection
Axon
Dendrite
Predominantly Localized To The Later Golgi/Trans-Golgi Network (Tgn) And Minimally Detectable In The Early Golgi Compartments
A Small Portion Is Also Found In The Endoplasmic Reticulum
Endosomes And On The Cell Surface
Colocalization With App In Early Endosomes Is Due To Addition Of Bisecting N-Acetylglucosamine Wich Blocks Targeting To Late Endosomes And Lysosomes (By Similarity)
Retrogradly Transported From Endosomal Compartments To The Trans-Golgi Network In A Phosphorylation-And Gga1-Dependent Manner

IHC 1:100-1:300
IF 1:200-1:1000
ELISA 1:5000

Beta-Secretase 1
Aspartyl Protease 2
Asp2
Asp 2
Beta-Site Amyloid Precursor Protein Cleaving Enzyme 1
Beta-Site App Cleaving Enzyme 1
Memapsin-2
Membrane-Associated Aspartic Protease 2

BACE1_HUMAN