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Anti-BACE antibody

Anti-BACE antibody

Manufacturer	St John's Laboratory
Category	Oncology Neuroscience Molecular Targets for Neuroscience Aging & Neurological Disorders Protein Aggregation, Clearance & Misfolding Antibodies By Cell Type Adenocarcinoma Immunohistochemistry ELISA Immunofluorescence Primary Antibodies
Type	Antibody Polyclonal
Specific against	Human, Mouse, Rat
Isotype	IgG
Applications	IF, ELISA, IHC-P
Amount	50ul
Host	Rabbit
Item no.	STJ91795-50
eClass 6.1	32160702
eClass 9.0	32160702
Available
Clonality	Polyclonal
Conjugation	Unconjugated
Formulation	Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Purification	The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Uniprot ID	P56817
Storage	Store at-20° C, and avoid repeat freeze-thaw cycles.
Concentration	1 mg/ml
Description	Rabbit polyclonal to BACE.
Gene ID	23621
Gene symbol	BACE1
Immunogen	Synthesized peptide derived from human BACE around the non-phosphorylation site of S498.
Immunogen region	440-520 aa
Short Description	Rabbit polyclonal against BACE
Tissue specificity	Expressed at high levels in the brain and pancreas. In the brain, expression is highest in the substantia nigra, locus coruleus and medulla oblongata.
Cellular localization	Cell Membrane Single-Pass Type I Membrane Protein Golgi Apparatus Trans-Golgi Network Endoplasmic Reticulum Endosome Cell Surface Cytoplasmic Vesicle Membrane Membrane Raft Lysosome Late Endosome Early Endosome Recycling Endosome Cell Projection Axon Dendrite Predominantly Localized To The Later Golgi/Trans-Golgi Network (Tgn) And Minimally Detectable In The Early Golgi Compartments A Small Portion Is Also Found In The Endoplasmic Reticulum Endosomes And On The Cell Surface Colocalization With App In Early Endosomes Is Due To Addition Of Bisecting N-Acetylglucosamine Wich Blocks Targeting To Late Endosomes And Lysosomes (By Similarity) Retrogradly Transported From Endosomal Compartments To The Trans-Golgi Network In A Phosphorylation-And Gga1-Dependent Manner
Molecular weight	55.764 kDa
Dilution range	IHC 1:100-1:300 IF 1:200-1:1000 ELISA 1:5000
Alternative names	Anti-Beta-Secretase 1 antibody Anti-Aspartyl Protease 2 antibody Anti-Asp2 antibody Anti-Asp 2 antibody Anti-Beta-Site Amyloid Precursor Protein Cleaving Enzyme 1 antibody Anti-Beta-Site App Cleaving Enzyme 1 antibody Anti-Memapsin-2 antibody Anti-Membrane-Associated Aspartic Protease 2 antibody Anti-BACE1 BACE KIAA1149 antibody
Protein name	Beta-Secretase 1 Aspartyl Protease 2 Asp2 Asp 2 Beta-Site Amyloid Precursor Protein Cleaving Enzyme 1 Beta-Site App Cleaving Enzyme 1 Memapsin-2 Membrane-Associated Aspartic Protease 2
Note	FOR RESEARCH USE ONLY (RUO).
Swiss port key	BACE1_HUMAN

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 50ul

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Delivery expected until 5/23/2024